UBE4B promotes gastric cancer proliferation and metastasis by mediating FAT4 ubiquitination and degradation
Abstract The ubiquitin‒proteasome system (UPS), an intracellular protein degradation pathway, plays an important role in regulating tumorigenesis and development. Ubiquitination factor E4B (UBE4B/UFD2) has been shown to be associated with the development of several cancers. The aim of this study was...
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| Main Authors: | Kaini Wu, Zixiang Guo, Yunfeng Fu, Sicheng Yang, Yating Pan, Runwei Yan, Xiaodong Zhou |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-07-01
|
| Series: | Cell Death and Disease |
| Online Access: | https://doi.org/10.1038/s41419-025-07794-8 |
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