An uneventful pregnancy and delivery, in a case with chronic myeloid leukemia on imatinib
The concomitant occurrence of pregnancy and chronic myelogenous leukemia is uncommon. We describe the successful management of a 24-year-old woman in the first trimester of her pregnancy with chronic myelogenous leukemia (CML) in the chronic phase, who was on treatment with imatinib, which was stopp...
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2011-01-01
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| Series: | Indian Journal of Medical and Paediatric Oncology |
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| Online Access: | http://www.ijmpo.org/article.asp?issn=0971-5851;year=2011;volume=32;issue=2;spage=109;epage=111;aulast=Martin |
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| _version_ | 1849315717792399360 |
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| author | Jovita Martin Anita Ramesh Lalitha Devadasan Palaniappan Jude J Martin |
| author_facet | Jovita Martin Anita Ramesh Lalitha Devadasan Palaniappan Jude J Martin |
| author_sort | Jovita Martin |
| collection | DOAJ |
| description | The concomitant occurrence of pregnancy and chronic myelogenous leukemia is uncommon. We describe the successful management of a 24-year-old woman in the first trimester of her pregnancy with chronic myelogenous leukemia (CML) in the chronic phase, who was on treatment with imatinib, which was stopped by 10 th week of pregnancy. Until, she completed full term of pregnancy she was on hydroxyurea. The use of imatinib did not have adverse effects on the fetus. The patient had a normal vaginal delivery and gave birth to a healthy 2500 g girl at 37 weeks of gestation. We conclude that imatinib in the first trimester of pregnant lady with CML, though has particular concern regarding the potential teratogenic and other adverse effects, has shown evidences of safe conception, pregnancy and delivery in ladies with CML. |
| format | Article |
| id | doaj-art-e7ed601f20f64b639552d247a55f718a |
| institution | Kabale University |
| issn | 0971-5851 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Indian Journal of Medical and Paediatric Oncology |
| spelling | doaj-art-e7ed601f20f64b639552d247a55f718a2025-08-20T03:52:04ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58512011-01-0132210911110.4103/0971-5851.89795An uneventful pregnancy and delivery, in a case with chronic myeloid leukemia on imatinibJovita MartinAnita RameshLalitha DevadasanPalaniappanJude J MartinThe concomitant occurrence of pregnancy and chronic myelogenous leukemia is uncommon. We describe the successful management of a 24-year-old woman in the first trimester of her pregnancy with chronic myelogenous leukemia (CML) in the chronic phase, who was on treatment with imatinib, which was stopped by 10 th week of pregnancy. Until, she completed full term of pregnancy she was on hydroxyurea. The use of imatinib did not have adverse effects on the fetus. The patient had a normal vaginal delivery and gave birth to a healthy 2500 g girl at 37 weeks of gestation. We conclude that imatinib in the first trimester of pregnant lady with CML, though has particular concern regarding the potential teratogenic and other adverse effects, has shown evidences of safe conception, pregnancy and delivery in ladies with CML.http://www.ijmpo.org/article.asp?issn=0971-5851;year=2011;volume=32;issue=2;spage=109;epage=111;aulast=MartinCML in pregnancyimatinib in pregnancysafety of imatinib in pregnancy |
| spellingShingle | Jovita Martin Anita Ramesh Lalitha Devadasan Palaniappan Jude J Martin An uneventful pregnancy and delivery, in a case with chronic myeloid leukemia on imatinib Indian Journal of Medical and Paediatric Oncology CML in pregnancy imatinib in pregnancy safety of imatinib in pregnancy |
| title | An uneventful pregnancy and delivery, in a case with chronic myeloid leukemia on imatinib |
| title_full | An uneventful pregnancy and delivery, in a case with chronic myeloid leukemia on imatinib |
| title_fullStr | An uneventful pregnancy and delivery, in a case with chronic myeloid leukemia on imatinib |
| title_full_unstemmed | An uneventful pregnancy and delivery, in a case with chronic myeloid leukemia on imatinib |
| title_short | An uneventful pregnancy and delivery, in a case with chronic myeloid leukemia on imatinib |
| title_sort | uneventful pregnancy and delivery in a case with chronic myeloid leukemia on imatinib |
| topic | CML in pregnancy imatinib in pregnancy safety of imatinib in pregnancy |
| url | http://www.ijmpo.org/article.asp?issn=0971-5851;year=2011;volume=32;issue=2;spage=109;epage=111;aulast=Martin |
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