Phenytoin induced dystonia

The abnormalities of dopaminergic activity in the basal ganglia have been emphasized to be effective in dystonia. We hereby report a case of a 2.5-year-old male patient who presented with tonic-clonic sezures and who developed dystonia after being given phenytoin. Biperidene hydrochloride was admin...

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Main Authors: Tarık Acar, Gülsüm Alkan, Hüseyin Çaksen, Birsen Ertekin, Mehmet Ergin, Sedat Koçak, Başar Cander
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2018-02-01
Series:The Turkish Journal of Pediatrics
Subjects:
Online Access:https://turkjpediatr.org/article/view/825
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author Tarık Acar
Gülsüm Alkan
Hüseyin Çaksen
Birsen Ertekin
Mehmet Ergin
Sedat Koçak
Başar Cander
author_facet Tarık Acar
Gülsüm Alkan
Hüseyin Çaksen
Birsen Ertekin
Mehmet Ergin
Sedat Koçak
Başar Cander
author_sort Tarık Acar
collection DOAJ
description The abnormalities of dopaminergic activity in the basal ganglia have been emphasized to be effective in dystonia. We hereby report a case of a 2.5-year-old male patient who presented with tonic-clonic sezures and who developed dystonia after being given phenytoin. Biperidene hydrochloride was administered intramuscularly; primidone was added to the treatment regimen. After a 7-day-follow-up at the hospital, the patient had no dystonia and was discharged.
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institution DOAJ
issn 0041-4301
2791-6421
language English
publishDate 2018-02-01
publisher Hacettepe University Institute of Child Health
record_format Article
series The Turkish Journal of Pediatrics
spelling doaj-art-e7eafd02131546f2bd4c7e9d2fdf28c02025-08-20T02:55:38ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212018-02-0160110.24953/turkjped.2018.01.019Phenytoin induced dystoniaTarık Acar0Gülsüm Alkan1Hüseyin Çaksen2Birsen Ertekin3Mehmet Ergin4Sedat Koçak5Başar Cander6Department of Emergency Medicine, Beyhekim State Hospital, Konya, Turkey.Departments of Pediatrics, Necmettin Erbakan University Meram Faculty of Medicine, Konya, Turkey.Departments of Pediatrics, Necmettin Erbakan University Meram Faculty of Medicine, Konya, Turkey.Department of Emergency Medicine, Beyhekim State Hospital, Konya, Turkey.Departments of Emergency Medicine, Necmettin Erbakan University Meram Faculty of Medicine, Konya, Turkey.Departments of Emergency Medicine, Necmettin Erbakan University Meram Faculty of Medicine, Konya, Turkey.Departments of Emergency Medicine, Necmettin Erbakan University Meram Faculty of Medicine, Konya, Turkey. The abnormalities of dopaminergic activity in the basal ganglia have been emphasized to be effective in dystonia. We hereby report a case of a 2.5-year-old male patient who presented with tonic-clonic sezures and who developed dystonia after being given phenytoin. Biperidene hydrochloride was administered intramuscularly; primidone was added to the treatment regimen. After a 7-day-follow-up at the hospital, the patient had no dystonia and was discharged. https://turkjpediatr.org/article/view/825dystoniaepilepsyphenytoin
spellingShingle Tarık Acar
Gülsüm Alkan
Hüseyin Çaksen
Birsen Ertekin
Mehmet Ergin
Sedat Koçak
Başar Cander
Phenytoin induced dystonia
The Turkish Journal of Pediatrics
dystonia
epilepsy
phenytoin
title Phenytoin induced dystonia
title_full Phenytoin induced dystonia
title_fullStr Phenytoin induced dystonia
title_full_unstemmed Phenytoin induced dystonia
title_short Phenytoin induced dystonia
title_sort phenytoin induced dystonia
topic dystonia
epilepsy
phenytoin
url https://turkjpediatr.org/article/view/825
work_keys_str_mv AT tarıkacar phenytoininduceddystonia
AT gulsumalkan phenytoininduceddystonia
AT huseyincaksen phenytoininduceddystonia
AT birsenertekin phenytoininduceddystonia
AT mehmetergin phenytoininduceddystonia
AT sedatkocak phenytoininduceddystonia
AT basarcander phenytoininduceddystonia