Peptic ulcer of gastrojejunal anastomosis: an undeservedly neglected problem
Aim. To evaluate the incidence and causes of peptic ulcers of the gastrojejunal anastomosis to develop the corresponding preventive measures.Materials and Methods. We retrospectively analysed the case histories of the patients with peptic ulcer who have been admitted to our surgical unit during 1981...
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Kemerovo State Medical University
2023-06-01
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| Series: | Фундаментальная и клиническая медицина |
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| Online Access: | https://fcm.kemsmu.ru/jour/article/view/718 |
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| author | V. I. Podoluzhnyi A. B. Startsev Yu. A. Kokoulina I. A. Radionov |
| author_facet | V. I. Podoluzhnyi A. B. Startsev Yu. A. Kokoulina I. A. Radionov |
| author_sort | V. I. Podoluzhnyi |
| collection | DOAJ |
| description | Aim. To evaluate the incidence and causes of peptic ulcers of the gastrojejunal anastomosis to develop the corresponding preventive measures.Materials and Methods. We retrospectively analysed the case histories of the patients with peptic ulcer who have been admitted to our surgical unit during 1981-1996 and 2007-2021. A total of 62 patients with peptic ulcers of the anastomosis who underwent Billroth II resection were examined radiographically, endoscopically, and intraoperatively, including proteolysis and acidity measurements.Results. While the number of gastric operations has been reduced by 86%, the number of treated peptic anastomotic ulcers decreased by only 20%. The main cause of peptic ulcers was the high acidity and proteolytic activity of the gastric stump. In 22 out of 28 fully examined patients, duodenal ulcer was treated by hemiresection. The incidence of peptic ulcers of gastrojejunal anastomosis in Kemerovo in 2021 was 0.9 per 100,000 population, with 3.7 Billroth II surgeries per 100,000 population. A resection without vagotomy and insufficient acid reduction are the main causes of peptic ulcers of the gastrointestinal anastomosis, especially duodenal ulcers.Conclusion. A significant decrease in the number of distal resections of the stomach according to Billroth II over the past 25 years is not accompanied by a similar decline in the number of hospitalized patients with peptic ulcers of the gastrojejunal anastomosis. |
| format | Article |
| id | doaj-art-e7df884532d9457da5144d10e998e6ab |
| institution | DOAJ |
| issn | 2500-0764 2542-0941 |
| language | Russian |
| publishDate | 2023-06-01 |
| publisher | Kemerovo State Medical University |
| record_format | Article |
| series | Фундаментальная и клиническая медицина |
| spelling | doaj-art-e7df884532d9457da5144d10e998e6ab2025-08-20T02:49:13ZrusKemerovo State Medical UniversityФундаментальная и клиническая медицина2500-07642542-09412023-06-0182879210.23946/2500-0764-2023-8-2-87-92371Peptic ulcer of gastrojejunal anastomosis: an undeservedly neglected problemV. I. Podoluzhnyi0A. B. Startsev1Yu. A. Kokoulina2I. A. Radionov3Kemerovo State Medical UniversityPodgorbunsky Regional Clinical Emergency HospitalKemerovo State Medical UniversityKemerovo State Medical UniversityAim. To evaluate the incidence and causes of peptic ulcers of the gastrojejunal anastomosis to develop the corresponding preventive measures.Materials and Methods. We retrospectively analysed the case histories of the patients with peptic ulcer who have been admitted to our surgical unit during 1981-1996 and 2007-2021. A total of 62 patients with peptic ulcers of the anastomosis who underwent Billroth II resection were examined radiographically, endoscopically, and intraoperatively, including proteolysis and acidity measurements.Results. While the number of gastric operations has been reduced by 86%, the number of treated peptic anastomotic ulcers decreased by only 20%. The main cause of peptic ulcers was the high acidity and proteolytic activity of the gastric stump. In 22 out of 28 fully examined patients, duodenal ulcer was treated by hemiresection. The incidence of peptic ulcers of gastrojejunal anastomosis in Kemerovo in 2021 was 0.9 per 100,000 population, with 3.7 Billroth II surgeries per 100,000 population. A resection without vagotomy and insufficient acid reduction are the main causes of peptic ulcers of the gastrointestinal anastomosis, especially duodenal ulcers.Conclusion. A significant decrease in the number of distal resections of the stomach according to Billroth II over the past 25 years is not accompanied by a similar decline in the number of hospitalized patients with peptic ulcers of the gastrojejunal anastomosis.https://fcm.kemsmu.ru/jour/article/view/718peptic ulcergastric resectionacidityproteolysisgastric stump |
| spellingShingle | V. I. Podoluzhnyi A. B. Startsev Yu. A. Kokoulina I. A. Radionov Peptic ulcer of gastrojejunal anastomosis: an undeservedly neglected problem Фундаментальная и клиническая медицина peptic ulcer gastric resection acidity proteolysis gastric stump |
| title | Peptic ulcer of gastrojejunal anastomosis: an undeservedly neglected problem |
| title_full | Peptic ulcer of gastrojejunal anastomosis: an undeservedly neglected problem |
| title_fullStr | Peptic ulcer of gastrojejunal anastomosis: an undeservedly neglected problem |
| title_full_unstemmed | Peptic ulcer of gastrojejunal anastomosis: an undeservedly neglected problem |
| title_short | Peptic ulcer of gastrojejunal anastomosis: an undeservedly neglected problem |
| title_sort | peptic ulcer of gastrojejunal anastomosis an undeservedly neglected problem |
| topic | peptic ulcer gastric resection acidity proteolysis gastric stump |
| url | https://fcm.kemsmu.ru/jour/article/view/718 |
| work_keys_str_mv | AT vipodoluzhnyi pepticulcerofgastrojejunalanastomosisanundeservedlyneglectedproblem AT abstartsev pepticulcerofgastrojejunalanastomosisanundeservedlyneglectedproblem AT yuakokoulina pepticulcerofgastrojejunalanastomosisanundeservedlyneglectedproblem AT iaradionov pepticulcerofgastrojejunalanastomosisanundeservedlyneglectedproblem |