Contrasting effects of acute versus chronic intermittent hypoxia on leptin secretion in differentiated human adipocytes – Implications for sleep apnea

Contrasting effects of acute versus chronic intermittent hypoxia on leptin secretion in differentiated human adipocytes – Implications for sleep apnea

Obstructive sleep apnea (OSA) is a common sleep disorder associated with repetitive episodes of nocturnal intermittent hypoxia (IH), obesity and elevated leptin. Newly diagnosed OSA patients have a history of significant recent weight gain. While IH is implicated in OSA pathophysiology, the factors...

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Bibliographic Details
Main Authors: Kiran R. Somers, Christiane Becari, Katarzyna Polonis, Prachi Singh
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Biochemistry and Biophysics Reports
Subjects:
Hypoxia
Adipocytes
Leptin
Sleep apnea
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580825001177
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