Sleep drive is coupled to tissue damage via shedding of Caenorhabditis elegans EGFR ligand SISS-1
Abstract The benefits of sleep extend beyond the nervous system. Peripheral tissues impact sleep regulation, and increased sleep is observed in response to damaging conditions, even those that selectively affect non-neuronal cells. However, the ‘sleep need’ signal released by stressed tissues is not...
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| Main Authors: | Andrew J. Hill, Bryan Robinson, Jesse G. Jones, Paul W. Sternberg, Cheryl Van Buskirk |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-12-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-024-55252-4 |
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