Antihypertensive Medication Adherence and Related Factors among Elderly Hypertensive Patients in China: A Meta-analysis

Background: Hypertension is one of the most common chronic diseases among elderly people, while medication adherence is associated with a decreased risk of complications in elderly hypertensive patients. Objectives: The purpose of this meta-analysis was to estimate the adherence to antihypertensive...

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Main Authors: Haiyan Liu, Xueqin Zuo, Zhikai Zhou, Yina Ma, Bin Wang, Xiuquan Shi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Indian Journal of Public Health
Subjects:
Online Access:https://journals.lww.com/10.4103/ijph.ijph_216_24
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author Haiyan Liu
Xueqin Zuo
Zhikai Zhou
Yina Ma
Bin Wang
Xiuquan Shi
author_facet Haiyan Liu
Xueqin Zuo
Zhikai Zhou
Yina Ma
Bin Wang
Xiuquan Shi
author_sort Haiyan Liu
collection DOAJ
description Background: Hypertension is one of the most common chronic diseases among elderly people, while medication adherence is associated with a decreased risk of complications in elderly hypertensive patients. Objectives: The purpose of this meta-analysis was to estimate the adherence to antihypertensive medication and related factors in elderly hypertensive patients in China. Materials and Methods: The databases served to retrieve the relevant literature before May 31, 2023. A systematic review (PROSPERO-CRD 42021278970) was conducted in accordance with PRISMA (Preferred Reporting Item for Systematic Reviews and Meta Analyses). Subgroup analysis, I2 statistics, publication bias, and quality assessment were conducted. Results: The prevalence of medication adherence among old hypertensive patients in China was 43% (95% confidence interval [CI]: 37%–49%). Medication adherence was related to education level (odds ratio [OR] = 2.12, 95% CI: 1.46-3.08), marriage (OR = 1.37,95% CI: 1.09–1.72) and the nonpresence of comorbidities (OR = 1.55, 95% CI: 1.11-2.16), but not related to the course of the disease ≤5 years (OR = 0.91,95% CI: 0.67-1.24). Adherence to antihypertensive medication among the old hypertensive population in China was moderate. Conclusion: Healthcare professionals should attach importance to older hypertension patients with low level of education and no spouse.
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spelling doaj-art-e7c90e6ba8b44cb29b58b12fe41fd8942025-08-20T02:15:41ZengWolters Kluwer Medknow PublicationsIndian Journal of Public Health0019-557X2229-76932025-01-01691829010.4103/ijph.ijph_216_24Antihypertensive Medication Adherence and Related Factors among Elderly Hypertensive Patients in China: A Meta-analysisHaiyan LiuXueqin ZuoZhikai ZhouYina MaBin WangXiuquan ShiBackground: Hypertension is one of the most common chronic diseases among elderly people, while medication adherence is associated with a decreased risk of complications in elderly hypertensive patients. Objectives: The purpose of this meta-analysis was to estimate the adherence to antihypertensive medication and related factors in elderly hypertensive patients in China. Materials and Methods: The databases served to retrieve the relevant literature before May 31, 2023. A systematic review (PROSPERO-CRD 42021278970) was conducted in accordance with PRISMA (Preferred Reporting Item for Systematic Reviews and Meta Analyses). Subgroup analysis, I2 statistics, publication bias, and quality assessment were conducted. Results: The prevalence of medication adherence among old hypertensive patients in China was 43% (95% confidence interval [CI]: 37%–49%). Medication adherence was related to education level (odds ratio [OR] = 2.12, 95% CI: 1.46-3.08), marriage (OR = 1.37,95% CI: 1.09–1.72) and the nonpresence of comorbidities (OR = 1.55, 95% CI: 1.11-2.16), but not related to the course of the disease ≤5 years (OR = 0.91,95% CI: 0.67-1.24). Adherence to antihypertensive medication among the old hypertensive population in China was moderate. Conclusion: Healthcare professionals should attach importance to older hypertension patients with low level of education and no spouse.https://journals.lww.com/10.4103/ijph.ijph_216_24agedchinahypertensionmedication adherencemeta-analysis
spellingShingle Haiyan Liu
Xueqin Zuo
Zhikai Zhou
Yina Ma
Bin Wang
Xiuquan Shi
Antihypertensive Medication Adherence and Related Factors among Elderly Hypertensive Patients in China: A Meta-analysis
Indian Journal of Public Health
aged
china
hypertension
medication adherence
meta-analysis
title Antihypertensive Medication Adherence and Related Factors among Elderly Hypertensive Patients in China: A Meta-analysis
title_full Antihypertensive Medication Adherence and Related Factors among Elderly Hypertensive Patients in China: A Meta-analysis
title_fullStr Antihypertensive Medication Adherence and Related Factors among Elderly Hypertensive Patients in China: A Meta-analysis
title_full_unstemmed Antihypertensive Medication Adherence and Related Factors among Elderly Hypertensive Patients in China: A Meta-analysis
title_short Antihypertensive Medication Adherence and Related Factors among Elderly Hypertensive Patients in China: A Meta-analysis
title_sort antihypertensive medication adherence and related factors among elderly hypertensive patients in china a meta analysis
topic aged
china
hypertension
medication adherence
meta-analysis
url https://journals.lww.com/10.4103/ijph.ijph_216_24
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AT yinama antihypertensivemedicationadherenceandrelatedfactorsamongelderlyhypertensivepatientsinchinaametaanalysis
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