The role of the endothelial dependent relaxing factor in the regulation of cerebral circulation
It has recently been demonstrated that vessel dilation induced by several physiological agents is dependent on an intact vascular endothelium. In order to explain this endothelium dependence, it has been hypothesized that a still unknown chemical substance, generically named Endothelium Dependent Re...
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações
1988-03-01
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| Series: | Arquivos de Neuro-Psiquiatria |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1988000100016&lng=en&tlng=en |
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| _version_ | 1850230514852560896 |
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| author | Antonio A. F. de Salles |
| author_facet | Antonio A. F. de Salles |
| author_sort | Antonio A. F. de Salles |
| collection | DOAJ |
| description | It has recently been demonstrated that vessel dilation induced by several physiological agents is dependent on an intact vascular endothelium. In order to explain this endothelium dependence, it has been hypothesized that a still unknown chemical substance, generically named Endothelium Dependent Relaxing Factor (EDRF) is necessary for physiological vasodilation. The role of this EDRF in the cerebrovascular physiology is not yet well understood. In this article the cerebrovascular physiological control is reviewed in relationship with possible EDRF actions. The importance of endothelial lesions in the cerebrovascular responses is discussed. |
| format | Article |
| id | doaj-art-e7c75de6065c45ed9bf2e12aa3ee4ed2 |
| institution | OA Journals |
| issn | 1678-4227 |
| language | English |
| publishDate | 1988-03-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-e7c75de6065c45ed9bf2e12aa3ee4ed22025-08-20T02:03:51ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42271988-03-01461909710.1590/S0004-282X1988000100016S0004-282X1988000100016The role of the endothelial dependent relaxing factor in the regulation of cerebral circulationAntonio A. F. de SallesIt has recently been demonstrated that vessel dilation induced by several physiological agents is dependent on an intact vascular endothelium. In order to explain this endothelium dependence, it has been hypothesized that a still unknown chemical substance, generically named Endothelium Dependent Relaxing Factor (EDRF) is necessary for physiological vasodilation. The role of this EDRF in the cerebrovascular physiology is not yet well understood. In this article the cerebrovascular physiological control is reviewed in relationship with possible EDRF actions. The importance of endothelial lesions in the cerebrovascular responses is discussed.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1988000100016&lng=en&tlng=en |
| spellingShingle | Antonio A. F. de Salles The role of the endothelial dependent relaxing factor in the regulation of cerebral circulation Arquivos de Neuro-Psiquiatria |
| title | The role of the endothelial dependent relaxing factor in the regulation of cerebral circulation |
| title_full | The role of the endothelial dependent relaxing factor in the regulation of cerebral circulation |
| title_fullStr | The role of the endothelial dependent relaxing factor in the regulation of cerebral circulation |
| title_full_unstemmed | The role of the endothelial dependent relaxing factor in the regulation of cerebral circulation |
| title_short | The role of the endothelial dependent relaxing factor in the regulation of cerebral circulation |
| title_sort | role of the endothelial dependent relaxing factor in the regulation of cerebral circulation |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1988000100016&lng=en&tlng=en |
| work_keys_str_mv | AT antonioafdesalles theroleoftheendothelialdependentrelaxingfactorintheregulationofcerebralcirculation AT antonioafdesalles roleoftheendothelialdependentrelaxingfactorintheregulationofcerebralcirculation |