Development of the plant collection prescription and the obtaining a liquid extract technology on its basis for prevention and treatment of musculoskeletal system diseases

Purpose. Development of the composition of the plant collection “Opornofit” and the technology of obtaining a liquid extract on its basis for the prevention and treatment of diseases of the musculoskeletal system, with the determination of quality indicators and stability during their storage. M...

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Main Authors: О. P. Khvorost, T. V. Oproshanska, K. S. Skrebtsova, O. S. Shpychak, A. M. Solomennyi, О. О. Davydenko, О. V. Golyuk
Format: Article
Language:English
Published: Ukrainian Military Medical Academy 2025-03-01
Series:Український журнал військової медицини
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Online Access:https://ujmm.org.ua/index.php/journal/article/view/525
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author О. P. Khvorost
T. V. Oproshanska
K. S. Skrebtsova
O. S. Shpychak
A. M. Solomennyi
О. О. Davydenko
О. V. Golyuk
author_facet О. P. Khvorost
T. V. Oproshanska
K. S. Skrebtsova
O. S. Shpychak
A. M. Solomennyi
О. О. Davydenko
О. V. Golyuk
author_sort О. P. Khvorost
collection DOAJ
description Purpose. Development of the composition of the plant collection “Opornofit” and the technology of obtaining a liquid extract on its basis for the prevention and treatment of diseases of the musculoskeletal system, with the determination of quality indicators and stability during their storage. Materials and methods. Plant raw materials for obtaining the collection and liquid extract from it were harvested in Vinnytsia and Kharkiv regions. The numerical parameters of the collection were determined according to the methods of the State Pharmacopoeia of Ukraine 2.0. Results. A screening of the range of medicinal plant raw materials, which in the form of mono- and polycomponent plant collections are used in phytotherapy of diseases of the musculoskeletal system, was carried out and the most promising types of plant raw materials were selected for creating the collection “Opornofit”: Arctium root (Arctium lappa L., Arctium minus (Hill) Bernh., Arctium tomentosum Mill.), Rose root (Rosa majalis Herrm., Rosa canina L.), rhizomes with roots of Sanguisorba officinalis L., rhizomes with roots of Rumex confertus Willd., and herb of Bidens tripartita L. with an equal ratio of components in the collection. Taking into account the conditions of military service and the frequent lack of conditions for preparing a decoction from the collection, we developed a technology for obtaining a liquid extract based on its components. For the developed collection and liquid extract, stability during storage during the year was studied. Conclusions. The composition of the herbal collection “Opornofit” and the technology for obtaining a liquid extract based on it for the prevention and treatment of diseases of the musculoskeletal system have been developed, with the determination of quality indicators and stability during their storage. The developed original herbal collection and liquid extract based on it are predicted to have anti-inflammatory, uricosuric, detoxifying, desensitizing, and immunostimulating effects.
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spelling doaj-art-e7bf22362ad34fd8a630c3e44a4aa6f12025-08-20T01:55:57ZengUkrainian Military Medical AcademyУкраїнський журнал військової медицини2708-66152708-66232025-03-016110.46847/ujmm.2025.1(6)-170Development of the plant collection prescription and the obtaining a liquid extract technology on its basis for prevention and treatment of musculoskeletal system diseasesО. P. Khvorost0T. V. Oproshanska1K. S. Skrebtsova2O. S. Shpychak3A. M. Solomennyi4О. О. Davydenko5О. V. Golyuk6National University of PharmacyNational University of PharmacyNational University of PharmacyNational University of PharmacyUkrainian Military Medical AcademyNational Pirogov Medical University VinnytsyaMilitary Medical Clinical Center of the Southern Region Purpose. Development of the composition of the plant collection “Opornofit” and the technology of obtaining a liquid extract on its basis for the prevention and treatment of diseases of the musculoskeletal system, with the determination of quality indicators and stability during their storage. Materials and methods. Plant raw materials for obtaining the collection and liquid extract from it were harvested in Vinnytsia and Kharkiv regions. The numerical parameters of the collection were determined according to the methods of the State Pharmacopoeia of Ukraine 2.0. Results. A screening of the range of medicinal plant raw materials, which in the form of mono- and polycomponent plant collections are used in phytotherapy of diseases of the musculoskeletal system, was carried out and the most promising types of plant raw materials were selected for creating the collection “Opornofit”: Arctium root (Arctium lappa L., Arctium minus (Hill) Bernh., Arctium tomentosum Mill.), Rose root (Rosa majalis Herrm., Rosa canina L.), rhizomes with roots of Sanguisorba officinalis L., rhizomes with roots of Rumex confertus Willd., and herb of Bidens tripartita L. with an equal ratio of components in the collection. Taking into account the conditions of military service and the frequent lack of conditions for preparing a decoction from the collection, we developed a technology for obtaining a liquid extract based on its components. For the developed collection and liquid extract, stability during storage during the year was studied. Conclusions. The composition of the herbal collection “Opornofit” and the technology for obtaining a liquid extract based on it for the prevention and treatment of diseases of the musculoskeletal system have been developed, with the determination of quality indicators and stability during their storage. The developed original herbal collection and liquid extract based on it are predicted to have anti-inflammatory, uricosuric, detoxifying, desensitizing, and immunostimulating effects. https://ujmm.org.ua/index.php/journal/article/view/525arctium, rosa, sanguisorba, rumex, bidens, herbal collection, musculoskeletal system.
spellingShingle О. P. Khvorost
T. V. Oproshanska
K. S. Skrebtsova
O. S. Shpychak
A. M. Solomennyi
О. О. Davydenko
О. V. Golyuk
Development of the plant collection prescription and the obtaining a liquid extract technology on its basis for prevention and treatment of musculoskeletal system diseases
Український журнал військової медицини
arctium, rosa, sanguisorba, rumex, bidens, herbal collection, musculoskeletal system.
title Development of the plant collection prescription and the obtaining a liquid extract technology on its basis for prevention and treatment of musculoskeletal system diseases
title_full Development of the plant collection prescription and the obtaining a liquid extract technology on its basis for prevention and treatment of musculoskeletal system diseases
title_fullStr Development of the plant collection prescription and the obtaining a liquid extract technology on its basis for prevention and treatment of musculoskeletal system diseases
title_full_unstemmed Development of the plant collection prescription and the obtaining a liquid extract technology on its basis for prevention and treatment of musculoskeletal system diseases
title_short Development of the plant collection prescription and the obtaining a liquid extract technology on its basis for prevention and treatment of musculoskeletal system diseases
title_sort development of the plant collection prescription and the obtaining a liquid extract technology on its basis for prevention and treatment of musculoskeletal system diseases
topic arctium, rosa, sanguisorba, rumex, bidens, herbal collection, musculoskeletal system.
url https://ujmm.org.ua/index.php/journal/article/view/525
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