Concentric and Eccentric Target MRI Signs in a Case of HIV-Associated Cerebral Toxoplasmosis

Cerebral toxoplasmosis is one of the most common causes of focal brain lesions in immunocompromised patients, such as those with human immunodeficiency virus (HIV). Differentiating toxoplasmosis from other central nervous system (CNS) lesions provides a significant clinical challenge. Magnetic reson...

Full description

Saved in:
Bibliographic Details
Main Authors: Adam D. Roche, Dominic Rowley, Francesca M. Brett, Seamus Looby
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Neurological Medicine
Online Access:http://dx.doi.org/10.1155/2018/9876514
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850163519791562752
author Adam D. Roche
Dominic Rowley
Francesca M. Brett
Seamus Looby
author_facet Adam D. Roche
Dominic Rowley
Francesca M. Brett
Seamus Looby
author_sort Adam D. Roche
collection DOAJ
description Cerebral toxoplasmosis is one of the most common causes of focal brain lesions in immunocompromised patients, such as those with human immunodeficiency virus (HIV). Differentiating toxoplasmosis from other central nervous system (CNS) lesions provides a significant clinical challenge. Magnetic resonance (MR) imaging of the brain is key to prompt diagnosis and treatment of cerebral toxoplasmosis. Several specific signs on MRI of brain have been described in recent literature including the “concentric target sign” and “eccentric target sign.” We report a case of successfully treated HIV-associated cerebral toxoplasmosis in which both MRI signs were present simultaneously.
format Article
id doaj-art-e7b8fdca58254c43b49ed91a8dd81990
institution OA Journals
issn 2090-6668
2090-6676
language English
publishDate 2018-01-01
publisher Wiley
record_format Article
series Case Reports in Neurological Medicine
spelling doaj-art-e7b8fdca58254c43b49ed91a8dd819902025-08-20T02:22:15ZengWileyCase Reports in Neurological Medicine2090-66682090-66762018-01-01201810.1155/2018/98765149876514Concentric and Eccentric Target MRI Signs in a Case of HIV-Associated Cerebral ToxoplasmosisAdam D. Roche0Dominic Rowley1Francesca M. Brett2Seamus Looby3Department of Radiology, Division of Neuroradiology, Beaumont Hospital, Dublin 9, IrelandThe GUIDE Clinic (Genitourinary and Infectious Disease Department), St. James Hospital, Dublin 8, IrelandDepartment of Neuropathology, Beaumont Hospital, Dublin 9, IrelandDepartment of Radiology, Division of Neuroradiology, Beaumont Hospital, Dublin 9, IrelandCerebral toxoplasmosis is one of the most common causes of focal brain lesions in immunocompromised patients, such as those with human immunodeficiency virus (HIV). Differentiating toxoplasmosis from other central nervous system (CNS) lesions provides a significant clinical challenge. Magnetic resonance (MR) imaging of the brain is key to prompt diagnosis and treatment of cerebral toxoplasmosis. Several specific signs on MRI of brain have been described in recent literature including the “concentric target sign” and “eccentric target sign.” We report a case of successfully treated HIV-associated cerebral toxoplasmosis in which both MRI signs were present simultaneously.http://dx.doi.org/10.1155/2018/9876514
spellingShingle Adam D. Roche
Dominic Rowley
Francesca M. Brett
Seamus Looby
Concentric and Eccentric Target MRI Signs in a Case of HIV-Associated Cerebral Toxoplasmosis
Case Reports in Neurological Medicine
title Concentric and Eccentric Target MRI Signs in a Case of HIV-Associated Cerebral Toxoplasmosis
title_full Concentric and Eccentric Target MRI Signs in a Case of HIV-Associated Cerebral Toxoplasmosis
title_fullStr Concentric and Eccentric Target MRI Signs in a Case of HIV-Associated Cerebral Toxoplasmosis
title_full_unstemmed Concentric and Eccentric Target MRI Signs in a Case of HIV-Associated Cerebral Toxoplasmosis
title_short Concentric and Eccentric Target MRI Signs in a Case of HIV-Associated Cerebral Toxoplasmosis
title_sort concentric and eccentric target mri signs in a case of hiv associated cerebral toxoplasmosis
url http://dx.doi.org/10.1155/2018/9876514
work_keys_str_mv AT adamdroche concentricandeccentrictargetmrisignsinacaseofhivassociatedcerebraltoxoplasmosis
AT dominicrowley concentricandeccentrictargetmrisignsinacaseofhivassociatedcerebraltoxoplasmosis
AT francescambrett concentricandeccentrictargetmrisignsinacaseofhivassociatedcerebraltoxoplasmosis
AT seamuslooby concentricandeccentrictargetmrisignsinacaseofhivassociatedcerebraltoxoplasmosis