Analytical assessment of metagenomic workflows for pathogen detection with NIST RM 8376 and two sample matrices
ABSTRACT We assessed the analytical performance of metagenomic workflows using NIST Reference Material (RM) 8376 DNA from bacterial pathogens spiked into two simulated clinical samples: cerebrospinal fluid (CSF) and stool. Sequencing and taxonomic classification were used to generate signals for eac...
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| Main Authors: | Jason G. Kralj, Stephanie L. Servetas, Samuel P. Forry, Monique E. Hunter, Jennifer N. Dootz, Scott A. Jackson |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2025-04-01
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| Series: | Microbiology Spectrum |
| Subjects: | |
| Online Access: | https://journals.asm.org/doi/10.1128/spectrum.02806-24 |
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