Quantitative analysis of the transcription control mechanism

Quantitative analysis of the transcription control mechanism

Abstract Gene transcription requires a sequence of promoter state transitions, including chromatin remodeling, assembly of the transcription machinery, and clearance of the promoter by RNA polymerase. The rate‐limiting steps in this sequence are regulated by transcriptional activators that bind at s...

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Bibliographic Details
Main Authors: Changhui Mao, Christopher R Brown, Elena Falkovskaia, Shawfeng Dong, Eva Hrabeta‐Robinson, Lauren Wenger, Hinrich Boeger
Format: Article
Language:English
Published: Springer Nature 2010-11-01
Series:Molecular Systems Biology
Subjects:
chromatin dynamics
expression noise
gene regulation
stochastic model
Online Access:https://doi.org/10.1038/msb.2010.83
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