Synthetic peptides as valuable and versatile tools for research: our 20 year journey in Chile
According to the International Union of Pure and Applied Chemistry (IUPAC), peptides are small proteins with a size between 2 and 50 amino acids residues. They are ubiquitous across the evolutionary scale, fulfilling a wide variety of functions, from immune system effectors in simple organisms to si...
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| Format: | Article |
| Language: | English |
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Open Exploration
2024-10-01
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| Series: | Exploration of Drug Science |
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| Online Access: | https://www.explorationpub.com/uploads/Article/A100870/100870.pdf |
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| author | Constanza Cárdenas Paula Santana Claudio Álvarez Luis Mercado Sergio Marshall Fernando Albericio Fanny Guzmán |
| author_facet | Constanza Cárdenas Paula Santana Claudio Álvarez Luis Mercado Sergio Marshall Fernando Albericio Fanny Guzmán |
| author_sort | Constanza Cárdenas |
| collection | DOAJ |
| description | According to the International Union of Pure and Applied Chemistry (IUPAC), peptides are small proteins with a size between 2 and 50 amino acids residues. They are ubiquitous across the evolutionary scale, fulfilling a wide variety of functions, from immune system effectors in simple organisms to signaling or neuromodulating agents in high vertebrates. Following nature’s example, peptides have emerged as alternatives in various fields. One particularly relevant area is in drug discovery, offering alternatives to face the emergence of antibiotic-resistant microorganisms. Peptides are also prevalent in other sectors, such as the food industry, where they serve as food additives to enhance nutritional characteristics or aid in food preservation. Moreover, peptides are increasingly being utilized in cosmetics. Additionally, peptides serve as valuable tools in both basic and applied research, facilitating the exploration of specific activity mechanisms and the verification of particular activities, among various other applications. Despite certain limitations and disadvantages compared to other bioactive molecules, peptides remain a focal point of interest in research, as well as in applied and developmental fields, due to their versatility. In this report, we provide an overview of the extensive application landscape of synthetic peptides, presenting examples developed in-house across different areas which include a summary of the methodologies and results obtained. |
| format | Article |
| id | doaj-art-e7a6286e87184771a7f3e8f7e1e40e21 |
| institution | Kabale University |
| issn | 2836-7677 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Open Exploration |
| record_format | Article |
| series | Exploration of Drug Science |
| spelling | doaj-art-e7a6286e87184771a7f3e8f7e1e40e212025-02-08T03:28:18ZengOpen ExplorationExploration of Drug Science2836-76772024-10-012570171810.37349/eds.2024.00070Synthetic peptides as valuable and versatile tools for research: our 20 year journey in ChileConstanza Cárdenas0https://orcid.org/0000-0002-3673-9320Paula Santana1https://orcid.org/0000-0002-5742-4926Claudio Álvarez2https://orcid.org/0000-0003-3132-2187Luis Mercado3https://orcid.org/0000-0003-3883-5188Sergio Marshall4https://orcid.org/0000-0003-0438-8252Fernando Albericio5https://orcid.org/0000-0002-8946-0462Fanny Guzmán6https://orcid.org/0000-0002-7829-0568Núcleo de Biotecnología Curauma, Pontificia Universidad Católica de Valparaíso, Valparaíso 2373223, ChileInstituto de Ciencias Aplicadas, Facultad de Ingeniería, Universidad Autónoma de Chile, Santiago 8910060, ChileLaboratorio de Cultivo de Peces Marinos, Departamento de Acuicultura, Universidad Católica del Norte, Coquimbo 1781421, Chile; Laboratorio de Fisiología y Genética Marina (FIGEMA), Centro de Estudios Avanzados en Zonas Áridas (CEAZA), Coquimbo 1781421, ChileLaboratorio de Patógenos Acuícolas, Instituto de Biología, Pontificia Universidad Católica de Valparaíso, Valparaíso 2373223, ChileLaboratorio de Genética e Inmunología Molecular, Instituto de Biología, Pontificia Universidad Católica de Valparaíso, Valparaíso 2373223, ChileDepartment of Organic Chemistry and CIBER‑BBN, Networking Centre on Bioengineering, Biomaterials and Nanomedicine, University of Barcelona, 08028 Barcelona, Spain; School of Chemistry and Physics, University of KwaZulu-Natal, Durban 4001, South AfricaNúcleo de Biotecnología Curauma, Pontificia Universidad Católica de Valparaíso, Valparaíso 2373223, ChileAccording to the International Union of Pure and Applied Chemistry (IUPAC), peptides are small proteins with a size between 2 and 50 amino acids residues. They are ubiquitous across the evolutionary scale, fulfilling a wide variety of functions, from immune system effectors in simple organisms to signaling or neuromodulating agents in high vertebrates. Following nature’s example, peptides have emerged as alternatives in various fields. One particularly relevant area is in drug discovery, offering alternatives to face the emergence of antibiotic-resistant microorganisms. Peptides are also prevalent in other sectors, such as the food industry, where they serve as food additives to enhance nutritional characteristics or aid in food preservation. Moreover, peptides are increasingly being utilized in cosmetics. Additionally, peptides serve as valuable tools in both basic and applied research, facilitating the exploration of specific activity mechanisms and the verification of particular activities, among various other applications. Despite certain limitations and disadvantages compared to other bioactive molecules, peptides remain a focal point of interest in research, as well as in applied and developmental fields, due to their versatility. In this report, we provide an overview of the extensive application landscape of synthetic peptides, presenting examples developed in-house across different areas which include a summary of the methodologies and results obtained.https://www.explorationpub.com/uploads/Article/A100870/100870.pdfantibodies generationbioactive peptidesbioprospectionantimicrobial peptides |
| spellingShingle | Constanza Cárdenas Paula Santana Claudio Álvarez Luis Mercado Sergio Marshall Fernando Albericio Fanny Guzmán Synthetic peptides as valuable and versatile tools for research: our 20 year journey in Chile Exploration of Drug Science antibodies generation bioactive peptides bioprospection antimicrobial peptides |
| title | Synthetic peptides as valuable and versatile tools for research: our 20 year journey in Chile |
| title_full | Synthetic peptides as valuable and versatile tools for research: our 20 year journey in Chile |
| title_fullStr | Synthetic peptides as valuable and versatile tools for research: our 20 year journey in Chile |
| title_full_unstemmed | Synthetic peptides as valuable and versatile tools for research: our 20 year journey in Chile |
| title_short | Synthetic peptides as valuable and versatile tools for research: our 20 year journey in Chile |
| title_sort | synthetic peptides as valuable and versatile tools for research our 20 year journey in chile |
| topic | antibodies generation bioactive peptides bioprospection antimicrobial peptides |
| url | https://www.explorationpub.com/uploads/Article/A100870/100870.pdf |
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