Chemokines simultaneously bind SARS-CoV-2 nucleocapsid protein RNA-binding and dimerization domains
Abstract Viruses express chemokine (CHK)-binding proteins to interfere with the host CHK network and thereby modulate leukocyte migration. SARS-CoV-2 Nucleocapsid (N) protein binds a subset of human CHKs with high affinity, inhibiting their chemoattractant properties. Here, we report that both N’s R...
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| Main Authors: | Alberto Domingo López-Muñoz, Jonathan W. Yewdell |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-03-01
|
| Series: | Virology Journal |
| Online Access: | https://doi.org/10.1186/s12985-025-02658-1 |
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