Endothelial function and vascular reactivity in workplace hypertension

Aim. To assess vascular reactivity and endothelial function (EF) in people with workplace hypertension (WPH) and arterial hypertension (AH) patients.Material and methods. Fifty men with Stage I-II AH were examined, including 30 with WPH, according to 24- hour blood pressure monitoring (BPM) during w...

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Main Authors: I. V. Osipova, O. N. Antropova, N. O. Glebov, G. A. Beloshapkina, T. V. Perevozchikova, N. M. Legkoshkurova
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2008-02-01
Series:Кардиоваскулярная терапия и профилактика
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Online Access:https://cardiovascular.elpub.ru/jour/article/view/1054
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author I. V. Osipova
O. N. Antropova
N. O. Glebov
G. A. Beloshapkina
T. V. Perevozchikova
N. M. Legkoshkurova
author_facet I. V. Osipova
O. N. Antropova
N. O. Glebov
G. A. Beloshapkina
T. V. Perevozchikova
N. M. Legkoshkurova
author_sort I. V. Osipova
collection DOAJ
description Aim. To assess vascular reactivity and endothelial function (EF) in people with workplace hypertension (WPH) and arterial hypertension (AH) patients.Material and methods. Fifty men with Stage I-II AH were examined, including 30 with WPH, according to 24- hour blood pressure monitoring (BPM) during workdays and weekends (20 subjects with low workplace stress levels). Mean age of the participants was 42,8±8,2 years. Cold stress test, psycho-mental reading test, and arithmetic counting (AC) test were performed. Healthy controls were 30 males (mean age 40,6±7,1 years). Endothelium- dependent vasodilatation (EDVD) was assessed during the cuff test.Results. BP reaction during stress tests was similar in all patients. During AC test, WPH patients demonstrated greater systolic blood pressure (SBP) increase than controls and AH patients. Increased cardiovascular reactivity during cold stress test was associated with AH in family history. In WPH subjects, EDVD was lower than in AH patients, and brachial artery occlusion was associated with vasoconstriction in 50%. Patients with cuff test vasoconstriction had lower SBP increase in cold stress test and greater SBP increase during reading test; diastolic BP (DBP) increase was greater in AC test. There was a negative correlation between DBP increase during AC test and EDVD. Conclusion. WPH patients differed from AH patients in terms of increased stress reactivity, associated with EF. Participants with cuff test vasoconstriction demonstrated vascular reactivity different from that in other AH patients.
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spelling doaj-art-e797fded34bb4b4f90d9e8421d3f483b2025-08-20T03:21:39Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252008-02-01711923767Endothelial function and vascular reactivity in workplace hypertensionI. V. Osipova0O. N. Antropova1N. O. Glebov2G. A. Beloshapkina3T. V. Perevozchikova4N. M. Legkoshkurova5Altay State Medical UniversityAltay State Medical UniversityAltay State Medical UniversityBarnaul Station Regional Clinical Hospital. BarnaulBarnaul Station Regional Clinical Hospital. BarnaulBarnaul Station Regional Clinical Hospital. BarnaulAim. To assess vascular reactivity and endothelial function (EF) in people with workplace hypertension (WPH) and arterial hypertension (AH) patients.Material and methods. Fifty men with Stage I-II AH were examined, including 30 with WPH, according to 24- hour blood pressure monitoring (BPM) during workdays and weekends (20 subjects with low workplace stress levels). Mean age of the participants was 42,8±8,2 years. Cold stress test, psycho-mental reading test, and arithmetic counting (AC) test were performed. Healthy controls were 30 males (mean age 40,6±7,1 years). Endothelium- dependent vasodilatation (EDVD) was assessed during the cuff test.Results. BP reaction during stress tests was similar in all patients. During AC test, WPH patients demonstrated greater systolic blood pressure (SBP) increase than controls and AH patients. Increased cardiovascular reactivity during cold stress test was associated with AH in family history. In WPH subjects, EDVD was lower than in AH patients, and brachial artery occlusion was associated with vasoconstriction in 50%. Patients with cuff test vasoconstriction had lower SBP increase in cold stress test and greater SBP increase during reading test; diastolic BP (DBP) increase was greater in AC test. There was a negative correlation between DBP increase during AC test and EDVD. Conclusion. WPH patients differed from AH patients in terms of increased stress reactivity, associated with EF. Participants with cuff test vasoconstriction demonstrated vascular reactivity different from that in other AH patients.https://cardiovascular.elpub.ru/jour/article/view/1054workplace hypertensionstress testsendothelial dysfunctionvascular reactivity
spellingShingle I. V. Osipova
O. N. Antropova
N. O. Glebov
G. A. Beloshapkina
T. V. Perevozchikova
N. M. Legkoshkurova
Endothelial function and vascular reactivity in workplace hypertension
Кардиоваскулярная терапия и профилактика
workplace hypertension
stress tests
endothelial dysfunction
vascular reactivity
title Endothelial function and vascular reactivity in workplace hypertension
title_full Endothelial function and vascular reactivity in workplace hypertension
title_fullStr Endothelial function and vascular reactivity in workplace hypertension
title_full_unstemmed Endothelial function and vascular reactivity in workplace hypertension
title_short Endothelial function and vascular reactivity in workplace hypertension
title_sort endothelial function and vascular reactivity in workplace hypertension
topic workplace hypertension
stress tests
endothelial dysfunction
vascular reactivity
url https://cardiovascular.elpub.ru/jour/article/view/1054
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AT onantropova endothelialfunctionandvascularreactivityinworkplacehypertension
AT noglebov endothelialfunctionandvascularreactivityinworkplacehypertension
AT gabeloshapkina endothelialfunctionandvascularreactivityinworkplacehypertension
AT tvperevozchikova endothelialfunctionandvascularreactivityinworkplacehypertension
AT nmlegkoshkurova endothelialfunctionandvascularreactivityinworkplacehypertension