Role of Lymphangiogenesis in Cardiac Repair and Regeneration

This article highlights the importance of the structure and function of cardiac lymphatics in cardiovascular diseases and the therapeutic potential of cardiac lymphangiogenesis. Specifically, we explore the innate lymphangiogenic response to damaged cardiac tissue or cardiac injury, derive key findi...

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Main Authors: Zhongyun Xu, Qing Lu, Liming Chen, Chengchao Ruan, Yingnan Bai, Yunzeng Zou, Junbo Ge
Format: Article
Language:English
Published: Houston Methodist DeBakey Heart & Vascular Center 2023-11-01
Series:Methodist DeBakey Cardiovascular Journal
Subjects:
Online Access:https://account.journal.houstonmethodist.org/index.php/up-j-mdbcj/article/view/1286
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author Zhongyun Xu
Qing Lu
Liming Chen
Chengchao Ruan
Yingnan Bai
Yunzeng Zou
Junbo Ge
author_facet Zhongyun Xu
Qing Lu
Liming Chen
Chengchao Ruan
Yingnan Bai
Yunzeng Zou
Junbo Ge
author_sort Zhongyun Xu
collection DOAJ
description This article highlights the importance of the structure and function of cardiac lymphatics in cardiovascular diseases and the therapeutic potential of cardiac lymphangiogenesis. Specifically, we explore the innate lymphangiogenic response to damaged cardiac tissue or cardiac injury, derive key findings from regenerative models demonstrating how robust lymphangiogenic responses can be supported to improve cardiac function, and introduce an approach to imaging the structure and function of cardiac lymphatics.
format Article
id doaj-art-e797fdb355a1456b9cd7fab349543b63
institution OA Journals
issn 1947-6108
language English
publishDate 2023-11-01
publisher Houston Methodist DeBakey Heart & Vascular Center
record_format Article
series Methodist DeBakey Cardiovascular Journal
spelling doaj-art-e797fdb355a1456b9cd7fab349543b632025-08-20T02:22:16ZengHouston Methodist DeBakey Heart & Vascular CenterMethodist DeBakey Cardiovascular Journal1947-61082023-11-01195374610.14797/mdcvj.12861263Role of Lymphangiogenesis in Cardiac Repair and RegenerationZhongyun Xu0https://orcid.org/0000-0002-7723-4951Qing Lu1https://orcid.org/0000-0001-5350-776XLiming Chen2Chengchao Ruan3https://orcid.org/0000-0001-5229-9428Yingnan Bai4https://orcid.org/0000-0002-8637-2301Yunzeng Zou5Junbo Ge6Shanghai East Hospital Tongji University, ShanghaiShanghai East Hospital Tongji University, ShanghaiFudan University, ShanghaiSchool of Basic Medical Sciences, Fudan University, ShanghaiZhongshan Hospital, Fudan University, ShanghaiZhongshan Hospital, Fudan University, ShanghaiZhongshan Hospital, Fudan University, Shanghai; National Clinical Research Center for Interventional Medicine, Shanghai; National Health Commission, Shanghai; Chinese Academy of Medical Sciences, ShanghaiThis article highlights the importance of the structure and function of cardiac lymphatics in cardiovascular diseases and the therapeutic potential of cardiac lymphangiogenesis. Specifically, we explore the innate lymphangiogenic response to damaged cardiac tissue or cardiac injury, derive key findings from regenerative models demonstrating how robust lymphangiogenic responses can be supported to improve cardiac function, and introduce an approach to imaging the structure and function of cardiac lymphatics.https://account.journal.houstonmethodist.org/index.php/up-j-mdbcj/article/view/1286cardiac lymphatic structurecardiac lymphangiogenesislymphatic visualization
spellingShingle Zhongyun Xu
Qing Lu
Liming Chen
Chengchao Ruan
Yingnan Bai
Yunzeng Zou
Junbo Ge
Role of Lymphangiogenesis in Cardiac Repair and Regeneration
Methodist DeBakey Cardiovascular Journal
cardiac lymphatic structure
cardiac lymphangiogenesis
lymphatic visualization
title Role of Lymphangiogenesis in Cardiac Repair and Regeneration
title_full Role of Lymphangiogenesis in Cardiac Repair and Regeneration
title_fullStr Role of Lymphangiogenesis in Cardiac Repair and Regeneration
title_full_unstemmed Role of Lymphangiogenesis in Cardiac Repair and Regeneration
title_short Role of Lymphangiogenesis in Cardiac Repair and Regeneration
title_sort role of lymphangiogenesis in cardiac repair and regeneration
topic cardiac lymphatic structure
cardiac lymphangiogenesis
lymphatic visualization
url https://account.journal.houstonmethodist.org/index.php/up-j-mdbcj/article/view/1286
work_keys_str_mv AT zhongyunxu roleoflymphangiogenesisincardiacrepairandregeneration
AT qinglu roleoflymphangiogenesisincardiacrepairandregeneration
AT limingchen roleoflymphangiogenesisincardiacrepairandregeneration
AT chengchaoruan roleoflymphangiogenesisincardiacrepairandregeneration
AT yingnanbai roleoflymphangiogenesisincardiacrepairandregeneration
AT yunzengzou roleoflymphangiogenesisincardiacrepairandregeneration
AT junboge roleoflymphangiogenesisincardiacrepairandregeneration