Relationship between physical parameters and visual analysis for assessment of image quality: a multi-center and multi-vendor phantom study in brain SPECT

Objective(s): Brain perfusion single-photon emission computed tomography (SPECT) image quality varies depending on SPECT systems. This study aimed to evaluate the relationship between physical parameters and visual analysis for assessment of the brain SPECT image quality. We conducted our phantom st...

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Main Authors: Akie Sugiura, Takayuki Shibutani, Masahisa Onoguchi, Akio Nagaki, Kotatsu Tsuboi, Toshimune Ito, Hajime Ichikawa
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2025-01-01
Series:Asia Oceania Journal of Nuclear Medicine and Biology
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Online Access:https://aojnmb.mums.ac.ir/article_24415_f2c99216f2dee2f1386aa511bbf42fa5.pdf
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author Akie Sugiura
Takayuki Shibutani
Masahisa Onoguchi
Akio Nagaki
Kotatsu Tsuboi
Toshimune Ito
Hajime Ichikawa
author_facet Akie Sugiura
Takayuki Shibutani
Masahisa Onoguchi
Akio Nagaki
Kotatsu Tsuboi
Toshimune Ito
Hajime Ichikawa
author_sort Akie Sugiura
collection DOAJ
description Objective(s): Brain perfusion single-photon emission computed tomography (SPECT) image quality varies depending on SPECT systems. This study aimed to evaluate the relationship between physical parameters and visual analysis for assessment of the brain SPECT image quality. We conducted our phantom study under various conditions in a multi-center and multi-vendor study.Methods: SPECT images of the brain phantom were acquired from eight devices in five institutions. The phantom was filled with 28 kBq/ml of 99mTc solution at the start of scanning. We obtained various data with different acquisition times under clinical reconstruction and acquisition conditions at each institution. Four physical parameters (percent contrast, contrast noise ratio (CNR), asymmetry index (AI), and sharpness index (SI)) were measured with the phantom. Seven observers blindly evaluated all image series and scored them on a scale of 1–3 using four checkpoints: contrast, image noise, symmetry, and sharpness. The average score for all observers was calculated.Results: CNR increased with increasing visual analysis scores for contrast and image noise, both of which were significantly different between the group with scores “<2” and the group with scores “≥2 and <3”. AI decreased as the visual analysis score for symmetry increased, and the AI of both groups with scores “≥2 and <3” and “3” were significantly lower than that of the group with scores “<2”. Conversely, no relationship with visual analysis was found for percent contrast and SI.Conclusion: We clarified the relationship between physical parameters and visual analysis of a brain phantom in a multi-center and multi-vendor study. CNR and AI showed agreement with visual analysis.
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spelling doaj-art-e78d59343b0b4c5c8dd3f63ac72b66e42025-08-20T02:38:03ZengMashhad University of Medical SciencesAsia Oceania Journal of Nuclear Medicine and Biology2322-57182322-57262025-01-01131425210.22038/aojnmb.2024.75204.152424415Relationship between physical parameters and visual analysis for assessment of image quality: a multi-center and multi-vendor phantom study in brain SPECTAkie Sugiura0Takayuki Shibutani1Masahisa Onoguchi2Akio Nagaki3Kotatsu Tsuboi4Toshimune Ito5Hajime Ichikawa6Department of Quantum Medical Technology, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Ishikawa, JapanDepartment of Quantum Medical Technology, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Ishikawa, JapanDepartment of Quantum Medical Technology, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Ishikawa, JapanDepartment of Radiological Technology, Kurashiki Central Hospital, Okayama, JapanDepartment of Radiological Technology, Hamamatsu Red Cross Hospital, Shizuoka, JapanDepartment of Radiological Technology, Faculty of Medical Technology, Tokyo, JapanDepartment of Radiology, Toyohashi Municipal Hospital, Aichi, JapanObjective(s): Brain perfusion single-photon emission computed tomography (SPECT) image quality varies depending on SPECT systems. This study aimed to evaluate the relationship between physical parameters and visual analysis for assessment of the brain SPECT image quality. We conducted our phantom study under various conditions in a multi-center and multi-vendor study.Methods: SPECT images of the brain phantom were acquired from eight devices in five institutions. The phantom was filled with 28 kBq/ml of 99mTc solution at the start of scanning. We obtained various data with different acquisition times under clinical reconstruction and acquisition conditions at each institution. Four physical parameters (percent contrast, contrast noise ratio (CNR), asymmetry index (AI), and sharpness index (SI)) were measured with the phantom. Seven observers blindly evaluated all image series and scored them on a scale of 1–3 using four checkpoints: contrast, image noise, symmetry, and sharpness. The average score for all observers was calculated.Results: CNR increased with increasing visual analysis scores for contrast and image noise, both of which were significantly different between the group with scores “<2” and the group with scores “≥2 and <3”. AI decreased as the visual analysis score for symmetry increased, and the AI of both groups with scores “≥2 and <3” and “3” were significantly lower than that of the group with scores “<2”. Conversely, no relationship with visual analysis was found for percent contrast and SI.Conclusion: We clarified the relationship between physical parameters and visual analysis of a brain phantom in a multi-center and multi-vendor study. CNR and AI showed agreement with visual analysis.https://aojnmb.mums.ac.ir/article_24415_f2c99216f2dee2f1386aa511bbf42fa5.pdfbrain perfusion spectmulti-centermulti-vendorphysical parametervisual analysis
spellingShingle Akie Sugiura
Takayuki Shibutani
Masahisa Onoguchi
Akio Nagaki
Kotatsu Tsuboi
Toshimune Ito
Hajime Ichikawa
Relationship between physical parameters and visual analysis for assessment of image quality: a multi-center and multi-vendor phantom study in brain SPECT
Asia Oceania Journal of Nuclear Medicine and Biology
brain perfusion spect
multi-center
multi-vendor
physical parameter
visual analysis
title Relationship between physical parameters and visual analysis for assessment of image quality: a multi-center and multi-vendor phantom study in brain SPECT
title_full Relationship between physical parameters and visual analysis for assessment of image quality: a multi-center and multi-vendor phantom study in brain SPECT
title_fullStr Relationship between physical parameters and visual analysis for assessment of image quality: a multi-center and multi-vendor phantom study in brain SPECT
title_full_unstemmed Relationship between physical parameters and visual analysis for assessment of image quality: a multi-center and multi-vendor phantom study in brain SPECT
title_short Relationship between physical parameters and visual analysis for assessment of image quality: a multi-center and multi-vendor phantom study in brain SPECT
title_sort relationship between physical parameters and visual analysis for assessment of image quality a multi center and multi vendor phantom study in brain spect
topic brain perfusion spect
multi-center
multi-vendor
physical parameter
visual analysis
url https://aojnmb.mums.ac.ir/article_24415_f2c99216f2dee2f1386aa511bbf42fa5.pdf
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