Mitochondrial dysfunction is a key link involved in the pathogenesis of sick sinus syndrome: a review

Mitochondrial dysfunction is a key link involved in the pathogenesis of sick sinus syndrome: a review

Sick sinus syndrome (SSS) is a grave medical condition that can precipitate sudden death. The pathogenesis of SSS remains incompletely understood. Existing research postulates that the fundamental mechanism involves increased fibrosis of the sinoatrial node and its surrounding tissues, as well as di...

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Bibliographic Details
Main Authors: Xinxin Shi, Liming He, Yucheng Wang, Yue Wu, Dongming Lin, Chao Chen, Ming Yang, Shuwei Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Ca2+ clock
fibrosis
ion channel protein
membrane clock
mitochondria
review
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2024.1488207/full
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