Comparison of Differentially Expressed Genes in Human Versus in Chimeric Mouse Livers Following HBV Infection

Comparison of Differentially Expressed Genes in Human Versus in Chimeric Mouse Livers Following HBV Infection

Background/Objectives: Hepatitis B virus (HBV) infection is a worldwide health problem responsible for chronic liver disease and hepatocellular carcinoma. Both innate immunity and the adaptive immune response play central roles in the development of chronic hepatitis and liver cancer. We previously...

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Main Authors: Huarui Bao, Masataka Tsuge, Serami Murakami, Yasutoshi Fujii, Shinsuke Uchikawa, Hatsue Fujino, Atsushi Ono, Eisuke Murakami, Tomokazu Kawaoka, Daiki Miki, Clair Nelson Hayes, Shiro Oka
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Livers
Subjects:
hepatitis B virus (HBV)
human hepatocyte
gene expression
next-generation sequencing
DEGs
immune response
Online Access:https://www.mdpi.com/2673-4389/5/2/18
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