Use of two-part regression calibration model to correct for measurement error in episodically consumed foods in a single-replicate study design: EPIC case study.

In epidemiologic studies, measurement error in dietary variables often attenuates association between dietary intake and disease occurrence. To adjust for the attenuation caused by error in dietary intake, regression calibration is commonly used. To apply regression calibration, unbiased reference m...

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Main Authors: George O Agogo, Hilko van der Voet, Pieter van't Veer, Pietro Ferrari, Max Leenders, David C Muller, Emilio Sánchez-Cantalejo, Christina Bamia, Tonje Braaten, Sven Knüppel, Ingegerd Johansson, Fred A van Eeuwijk, Hendriek Boshuizen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0113160
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author George O Agogo
Hilko van der Voet
Pieter van't Veer
Pietro Ferrari
Max Leenders
David C Muller
Emilio Sánchez-Cantalejo
Christina Bamia
Tonje Braaten
Sven Knüppel
Ingegerd Johansson
Fred A van Eeuwijk
Hendriek Boshuizen
author_facet George O Agogo
Hilko van der Voet
Pieter van't Veer
Pietro Ferrari
Max Leenders
David C Muller
Emilio Sánchez-Cantalejo
Christina Bamia
Tonje Braaten
Sven Knüppel
Ingegerd Johansson
Fred A van Eeuwijk
Hendriek Boshuizen
author_sort George O Agogo
collection DOAJ
description In epidemiologic studies, measurement error in dietary variables often attenuates association between dietary intake and disease occurrence. To adjust for the attenuation caused by error in dietary intake, regression calibration is commonly used. To apply regression calibration, unbiased reference measurements are required. Short-term reference measurements for foods that are not consumed daily contain excess zeroes that pose challenges in the calibration model. We adapted two-part regression calibration model, initially developed for multiple replicates of reference measurements per individual to a single-replicate setting. We showed how to handle excess zero reference measurements by two-step modeling approach, how to explore heteroscedasticity in the consumed amount with variance-mean graph, how to explore nonlinearity with the generalized additive modeling (GAM) and the empirical logit approaches, and how to select covariates in the calibration model. The performance of two-part calibration model was compared with the one-part counterpart. We used vegetable intake and mortality data from European Prospective Investigation on Cancer and Nutrition (EPIC) study. In the EPIC, reference measurements were taken with 24-hour recalls. For each of the three vegetable subgroups assessed separately, correcting for error with an appropriately specified two-part calibration model resulted in about three fold increase in the strength of association with all-cause mortality, as measured by the log hazard ratio. Further found is that the standard way of including covariates in the calibration model can lead to over fitting the two-part calibration model. Moreover, the extent of adjusting for error is influenced by the number and forms of covariates in the calibration model. For episodically consumed foods, we advise researchers to pay special attention to response distribution, nonlinearity, and covariate inclusion in specifying the calibration model.
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spelling doaj-art-e7854ff38ec84e01af4cfa1bd188e0112025-08-20T02:22:37ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-01911e11316010.1371/journal.pone.0113160Use of two-part regression calibration model to correct for measurement error in episodically consumed foods in a single-replicate study design: EPIC case study.George O AgogoHilko van der VoetPieter van't VeerPietro FerrariMax LeendersDavid C MullerEmilio Sánchez-CantalejoChristina BamiaTonje BraatenSven KnüppelIngegerd JohanssonFred A van EeuwijkHendriek BoshuizenIn epidemiologic studies, measurement error in dietary variables often attenuates association between dietary intake and disease occurrence. To adjust for the attenuation caused by error in dietary intake, regression calibration is commonly used. To apply regression calibration, unbiased reference measurements are required. Short-term reference measurements for foods that are not consumed daily contain excess zeroes that pose challenges in the calibration model. We adapted two-part regression calibration model, initially developed for multiple replicates of reference measurements per individual to a single-replicate setting. We showed how to handle excess zero reference measurements by two-step modeling approach, how to explore heteroscedasticity in the consumed amount with variance-mean graph, how to explore nonlinearity with the generalized additive modeling (GAM) and the empirical logit approaches, and how to select covariates in the calibration model. The performance of two-part calibration model was compared with the one-part counterpart. We used vegetable intake and mortality data from European Prospective Investigation on Cancer and Nutrition (EPIC) study. In the EPIC, reference measurements were taken with 24-hour recalls. For each of the three vegetable subgroups assessed separately, correcting for error with an appropriately specified two-part calibration model resulted in about three fold increase in the strength of association with all-cause mortality, as measured by the log hazard ratio. Further found is that the standard way of including covariates in the calibration model can lead to over fitting the two-part calibration model. Moreover, the extent of adjusting for error is influenced by the number and forms of covariates in the calibration model. For episodically consumed foods, we advise researchers to pay special attention to response distribution, nonlinearity, and covariate inclusion in specifying the calibration model.https://doi.org/10.1371/journal.pone.0113160
spellingShingle George O Agogo
Hilko van der Voet
Pieter van't Veer
Pietro Ferrari
Max Leenders
David C Muller
Emilio Sánchez-Cantalejo
Christina Bamia
Tonje Braaten
Sven Knüppel
Ingegerd Johansson
Fred A van Eeuwijk
Hendriek Boshuizen
Use of two-part regression calibration model to correct for measurement error in episodically consumed foods in a single-replicate study design: EPIC case study.
PLoS ONE
title Use of two-part regression calibration model to correct for measurement error in episodically consumed foods in a single-replicate study design: EPIC case study.
title_full Use of two-part regression calibration model to correct for measurement error in episodically consumed foods in a single-replicate study design: EPIC case study.
title_fullStr Use of two-part regression calibration model to correct for measurement error in episodically consumed foods in a single-replicate study design: EPIC case study.
title_full_unstemmed Use of two-part regression calibration model to correct for measurement error in episodically consumed foods in a single-replicate study design: EPIC case study.
title_short Use of two-part regression calibration model to correct for measurement error in episodically consumed foods in a single-replicate study design: EPIC case study.
title_sort use of two part regression calibration model to correct for measurement error in episodically consumed foods in a single replicate study design epic case study
url https://doi.org/10.1371/journal.pone.0113160
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