OHIP-14 Scores in Patients with Sjögren’s Syndrome Compared to Sicca Syndrome: A Systematic Review with Meta-Analysis
Objectives. Primary Sjögren’s syndrome (pSS) is a chronic autoimmune disorder characterized by dryness of mucous membranes, predominantly the eyes and mouth, following glandular tissue substitution. The onset of oral dryness constitutes a significant source of discomfort that negatively affects over...
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | International Journal of Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2024/9277636 |
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| _version_ | 1849471805139451904 |
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| author | Rossana Izzetti Elisabetta Carli Stefano Gennai Filippo Graziani Marco Nisi |
| author_facet | Rossana Izzetti Elisabetta Carli Stefano Gennai Filippo Graziani Marco Nisi |
| author_sort | Rossana Izzetti |
| collection | DOAJ |
| description | Objectives. Primary Sjögren’s syndrome (pSS) is a chronic autoimmune disorder characterized by dryness of mucous membranes, predominantly the eyes and mouth, following glandular tissue substitution. The onset of oral dryness constitutes a significant source of discomfort that negatively affects overall quality of life. This systematic review aimed at investigating the differences in Oral Health Impact Profile-14 (OHIP-14) questionnaire scores in patients diagnosed with Sjögren’s syndrome compared to sicca syndrome, to assess the influence of the two conditions on oral health. Study Design. A systematic electronic and manual search was performed up to December 2023 for studies reporting OHIP-14 questionnaire scores in pSS patients versus sicca syndrome. Two authors independently reviewed, selected, and extracted the data. The outcome was the assessment of OHIP-14 scores in studies comparing pSS- and sicca syndrome-affected patients. Meta-analysis was conducted on available quantitative data. Results. Literature search retrieved 30 articles, and 3 articles met the criteria for inclusion in the review. Meta-analysis revealed significantly higher scores in patients with sicca syndrome compared to pSS, although salivary flow was markedly reduced in pSS. Conclusions. While offering supplementary information to standard tests and supporting the assessment of pSS and sicca syndrome patients, further validation is necessary to establish OHIP-14 validity in determining the impact of pSS and sicca syndrome on patients’ quality of life. |
| format | Article |
| id | doaj-art-e7836c8f3a894fd885d4d46333d8ebe8 |
| institution | Kabale University |
| issn | 1687-8736 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Dentistry |
| spelling | doaj-art-e7836c8f3a894fd885d4d46333d8ebe82025-08-20T03:24:43ZengWileyInternational Journal of Dentistry1687-87362024-01-01202410.1155/2024/9277636OHIP-14 Scores in Patients with Sjögren’s Syndrome Compared to Sicca Syndrome: A Systematic Review with Meta-AnalysisRossana Izzetti0Elisabetta Carli1Stefano Gennai2Filippo Graziani3Marco Nisi4Department of SurgicalUnit of Dentistry and Oral SurgeryDepartment of SurgicalDepartment of SurgicalDepartment of SurgicalObjectives. Primary Sjögren’s syndrome (pSS) is a chronic autoimmune disorder characterized by dryness of mucous membranes, predominantly the eyes and mouth, following glandular tissue substitution. The onset of oral dryness constitutes a significant source of discomfort that negatively affects overall quality of life. This systematic review aimed at investigating the differences in Oral Health Impact Profile-14 (OHIP-14) questionnaire scores in patients diagnosed with Sjögren’s syndrome compared to sicca syndrome, to assess the influence of the two conditions on oral health. Study Design. A systematic electronic and manual search was performed up to December 2023 for studies reporting OHIP-14 questionnaire scores in pSS patients versus sicca syndrome. Two authors independently reviewed, selected, and extracted the data. The outcome was the assessment of OHIP-14 scores in studies comparing pSS- and sicca syndrome-affected patients. Meta-analysis was conducted on available quantitative data. Results. Literature search retrieved 30 articles, and 3 articles met the criteria for inclusion in the review. Meta-analysis revealed significantly higher scores in patients with sicca syndrome compared to pSS, although salivary flow was markedly reduced in pSS. Conclusions. While offering supplementary information to standard tests and supporting the assessment of pSS and sicca syndrome patients, further validation is necessary to establish OHIP-14 validity in determining the impact of pSS and sicca syndrome on patients’ quality of life.http://dx.doi.org/10.1155/2024/9277636 |
| spellingShingle | Rossana Izzetti Elisabetta Carli Stefano Gennai Filippo Graziani Marco Nisi OHIP-14 Scores in Patients with Sjögren’s Syndrome Compared to Sicca Syndrome: A Systematic Review with Meta-Analysis International Journal of Dentistry |
| title | OHIP-14 Scores in Patients with Sjögren’s Syndrome Compared to Sicca Syndrome: A Systematic Review with Meta-Analysis |
| title_full | OHIP-14 Scores in Patients with Sjögren’s Syndrome Compared to Sicca Syndrome: A Systematic Review with Meta-Analysis |
| title_fullStr | OHIP-14 Scores in Patients with Sjögren’s Syndrome Compared to Sicca Syndrome: A Systematic Review with Meta-Analysis |
| title_full_unstemmed | OHIP-14 Scores in Patients with Sjögren’s Syndrome Compared to Sicca Syndrome: A Systematic Review with Meta-Analysis |
| title_short | OHIP-14 Scores in Patients with Sjögren’s Syndrome Compared to Sicca Syndrome: A Systematic Review with Meta-Analysis |
| title_sort | ohip 14 scores in patients with sjogren s syndrome compared to sicca syndrome a systematic review with meta analysis |
| url | http://dx.doi.org/10.1155/2024/9277636 |
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