From waste to health: exploring the male sexuality enhancing activities of the bioactive components of orange peel
Large amounts of citrus wastes, especially orange peels, are produced globally, and they are an environmental menace in different parts of the world because of their perishability. However, various research findings have shown that orange peels are a rich source of vitamins, fibers, phenols, and oth...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2025.1598545/full |
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| author | Adeyemi Fatai Odetayo Grace Edet Bassey Adenike Lizzy Adeyemi Luqman Aribidesi Olayaki |
| author_facet | Adeyemi Fatai Odetayo Grace Edet Bassey Adenike Lizzy Adeyemi Luqman Aribidesi Olayaki |
| author_sort | Adeyemi Fatai Odetayo |
| collection | DOAJ |
| description | Large amounts of citrus wastes, especially orange peels, are produced globally, and they are an environmental menace in different parts of the world because of their perishability. However, various research findings have shown that orange peels are a rich source of vitamins, fibers, phenols, and other bioactive compounds. This makes orange peel a promising therapeutic option for managing various disease conditions. Despite these health benefits, only about 10% of orange peel produced as waste is recycled and reused. Hence, the review was designed to explore the beneficial roles of orange peel bioactive compounds on male sexual function. This review, therefore, explore the aphrodisiac effect of orange peel bioactive compounds by reviewing recent publications that detail the association of orange peel bioactive compounds with male sexual functions regarding its potential roles in erectile function regulation, testosterone levels, and semen characteristics. Bioactive compounds from orange peel contributed positively to sexual and erectile functions. This was mediated via a hormonal-dependent mechanism and upregulation of steroidogenic enzymatic activities. It also improves endothelial functions by stimulating the secretion and release of nitric oxide, which is important for erection. Furthermore, it acts by mediating the activities of monoamine neurotransmitters, which are responsible for the motor activities involved in sexual function. Orange peel bioactive compounds enhance male sexual functions via multiple pathways. Hence, orange peels offer great potential for developing functional food products with health and economic benefits. |
| format | Article |
| id | doaj-art-e77f02c325034d899cfe6495daf3df4c |
| institution | OA Journals |
| issn | 1664-2392 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj-art-e77f02c325034d899cfe6495daf3df4c2025-08-20T02:36:00ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922025-07-011610.3389/fendo.2025.15985451598545From waste to health: exploring the male sexuality enhancing activities of the bioactive components of orange peelAdeyemi Fatai Odetayo0Grace Edet Bassey1Adenike Lizzy Adeyemi2Luqman Aribidesi Olayaki3Department of Physiology, Faculty of Basic Medical Sciences, Federal University of Health Sciences, Ila-Orangun, NigeriaDepartment of Medical Physiology, Faculty of Basic Medical Sciences, University of Uyo, Uyo, NigeriaEnvironmental Health and Safety, Osun State Ministry of Health, Osogbo, NigeriaDepartment of Physiology, University of Ilorin, Ilorin, NigeriaLarge amounts of citrus wastes, especially orange peels, are produced globally, and they are an environmental menace in different parts of the world because of their perishability. However, various research findings have shown that orange peels are a rich source of vitamins, fibers, phenols, and other bioactive compounds. This makes orange peel a promising therapeutic option for managing various disease conditions. Despite these health benefits, only about 10% of orange peel produced as waste is recycled and reused. Hence, the review was designed to explore the beneficial roles of orange peel bioactive compounds on male sexual function. This review, therefore, explore the aphrodisiac effect of orange peel bioactive compounds by reviewing recent publications that detail the association of orange peel bioactive compounds with male sexual functions regarding its potential roles in erectile function regulation, testosterone levels, and semen characteristics. Bioactive compounds from orange peel contributed positively to sexual and erectile functions. This was mediated via a hormonal-dependent mechanism and upregulation of steroidogenic enzymatic activities. It also improves endothelial functions by stimulating the secretion and release of nitric oxide, which is important for erection. Furthermore, it acts by mediating the activities of monoamine neurotransmitters, which are responsible for the motor activities involved in sexual function. Orange peel bioactive compounds enhance male sexual functions via multiple pathways. Hence, orange peels offer great potential for developing functional food products with health and economic benefits.https://www.frontiersin.org/articles/10.3389/fendo.2025.1598545/fullantioxidantcitrus peelerectile dysfunctionflavonoidsphenolic compoundstraditional medicine |
| spellingShingle | Adeyemi Fatai Odetayo Grace Edet Bassey Adenike Lizzy Adeyemi Luqman Aribidesi Olayaki From waste to health: exploring the male sexuality enhancing activities of the bioactive components of orange peel Frontiers in Endocrinology antioxidant citrus peel erectile dysfunction flavonoids phenolic compounds traditional medicine |
| title | From waste to health: exploring the male sexuality enhancing activities of the bioactive components of orange peel |
| title_full | From waste to health: exploring the male sexuality enhancing activities of the bioactive components of orange peel |
| title_fullStr | From waste to health: exploring the male sexuality enhancing activities of the bioactive components of orange peel |
| title_full_unstemmed | From waste to health: exploring the male sexuality enhancing activities of the bioactive components of orange peel |
| title_short | From waste to health: exploring the male sexuality enhancing activities of the bioactive components of orange peel |
| title_sort | from waste to health exploring the male sexuality enhancing activities of the bioactive components of orange peel |
| topic | antioxidant citrus peel erectile dysfunction flavonoids phenolic compounds traditional medicine |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2025.1598545/full |
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