Risk and Protective Factors for COVID-19 Infection among Pregnant Women with Sickle Cell Trait
Pregnant women and individuals with sickle cell trait (SCT) and underlying comorbidities are both independently more vulnerable to severe illness from coronavirus disease 2019 (COVID-19) compared to nonpregnant women and those without SCT. However, our understanding of the specific factors influenci...
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | Advances in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2024/1595091 |
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| author | Kim Abbegail Tan Aldecoa Camelia Arsene Geetha Krishnamoorthy Tiffany Chng Garrett Cherry Nabila Chowdhury Ryan Clark Dana Deeb Lisa Deptula Grey Dietz Ewomamobuho Eto Victoria Golston Landon Lawson Chioma Mbionwu Obiefuna Okponyia Jennifer Orejuela Thomaidha Qipo Sumit Raut Judie Goodman |
| author_facet | Kim Abbegail Tan Aldecoa Camelia Arsene Geetha Krishnamoorthy Tiffany Chng Garrett Cherry Nabila Chowdhury Ryan Clark Dana Deeb Lisa Deptula Grey Dietz Ewomamobuho Eto Victoria Golston Landon Lawson Chioma Mbionwu Obiefuna Okponyia Jennifer Orejuela Thomaidha Qipo Sumit Raut Judie Goodman |
| author_sort | Kim Abbegail Tan Aldecoa |
| collection | DOAJ |
| description | Pregnant women and individuals with sickle cell trait (SCT) and underlying comorbidities are both independently more vulnerable to severe illness from coronavirus disease 2019 (COVID-19) compared to nonpregnant women and those without SCT. However, our understanding of the specific factors influencing susceptibility to COVID-19 infection among pregnant women with SCT is currently constrained by limited available data. This study aims to determine the risk and protective factors that influence the likelihood of COVID-19 infection in this population. A retrospective analysis was done among 151 women with SCT in the reproductive age group. Multivariable analysis was performed to determine the various factors affecting COVID-19 infection among pregnant women with SCT. The study found that COVID-19-vaccinated pregnant women with SCT had a 90% lower risk of contracting COVID-19 and were 9 times more likely to have a COVID-19 infection if they had a history of pulmonary conditions such as asthma or chronic obstructive pulmonary disease. The present study further emphasizes the importance of the COVID-19 vaccine in preventing infection and safeguarding the health of pregnant women with SCT, particularly those with underlying comorbidities. |
| format | Article |
| id | doaj-art-e771cc76bfc6451bb311629ef6cfe9df |
| institution | OA Journals |
| issn | 1687-9112 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Hematology |
| spelling | doaj-art-e771cc76bfc6451bb311629ef6cfe9df2025-08-20T02:21:10ZengWileyAdvances in Hematology1687-91122024-01-01202410.1155/2024/1595091Risk and Protective Factors for COVID-19 Infection among Pregnant Women with Sickle Cell TraitKim Abbegail Tan Aldecoa0Camelia Arsene1Geetha Krishnamoorthy2Tiffany Chng3Garrett Cherry4Nabila Chowdhury5Ryan Clark6Dana Deeb7Lisa Deptula8Grey Dietz9Ewomamobuho Eto10Victoria Golston11Landon Lawson12Chioma Mbionwu13Obiefuna Okponyia14Jennifer Orejuela15Thomaidha Qipo16Sumit Raut17Judie Goodman18Department of Internal MedicineDepartment of Internal MedicineDepartment of Internal MedicineDepartment of Internal MedicineDepartment of Internal MedicineDepartment of Internal MedicineDepartment of Internal MedicineDepartment of Internal MedicineDepartment of Internal MedicineDepartment of Internal MedicineDepartment of Internal MedicineDepartment of Internal MedicineDepartment of Internal MedicineDepartment of Internal MedicineDepartment of Internal MedicineDepartment of Internal MedicineDepartment of Internal MedicineDepartment of Internal MedicineDepartment of Hematology and OncologyPregnant women and individuals with sickle cell trait (SCT) and underlying comorbidities are both independently more vulnerable to severe illness from coronavirus disease 2019 (COVID-19) compared to nonpregnant women and those without SCT. However, our understanding of the specific factors influencing susceptibility to COVID-19 infection among pregnant women with SCT is currently constrained by limited available data. This study aims to determine the risk and protective factors that influence the likelihood of COVID-19 infection in this population. A retrospective analysis was done among 151 women with SCT in the reproductive age group. Multivariable analysis was performed to determine the various factors affecting COVID-19 infection among pregnant women with SCT. The study found that COVID-19-vaccinated pregnant women with SCT had a 90% lower risk of contracting COVID-19 and were 9 times more likely to have a COVID-19 infection if they had a history of pulmonary conditions such as asthma or chronic obstructive pulmonary disease. The present study further emphasizes the importance of the COVID-19 vaccine in preventing infection and safeguarding the health of pregnant women with SCT, particularly those with underlying comorbidities.http://dx.doi.org/10.1155/2024/1595091 |
| spellingShingle | Kim Abbegail Tan Aldecoa Camelia Arsene Geetha Krishnamoorthy Tiffany Chng Garrett Cherry Nabila Chowdhury Ryan Clark Dana Deeb Lisa Deptula Grey Dietz Ewomamobuho Eto Victoria Golston Landon Lawson Chioma Mbionwu Obiefuna Okponyia Jennifer Orejuela Thomaidha Qipo Sumit Raut Judie Goodman Risk and Protective Factors for COVID-19 Infection among Pregnant Women with Sickle Cell Trait Advances in Hematology |
| title | Risk and Protective Factors for COVID-19 Infection among Pregnant Women with Sickle Cell Trait |
| title_full | Risk and Protective Factors for COVID-19 Infection among Pregnant Women with Sickle Cell Trait |
| title_fullStr | Risk and Protective Factors for COVID-19 Infection among Pregnant Women with Sickle Cell Trait |
| title_full_unstemmed | Risk and Protective Factors for COVID-19 Infection among Pregnant Women with Sickle Cell Trait |
| title_short | Risk and Protective Factors for COVID-19 Infection among Pregnant Women with Sickle Cell Trait |
| title_sort | risk and protective factors for covid 19 infection among pregnant women with sickle cell trait |
| url | http://dx.doi.org/10.1155/2024/1595091 |
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