Unexplained Hematocrit Increase after Therapeutic Phlebotomy in a Patient with Marked Erythrocytosis
We report a patient with hereditary erythrocytosis who underwent a therapeutic phlebotomy and had a post-phlebotomy hematocrit that was higher than the pre-phlebotomy hematocrit. We could not discern a reason for this hematocrit increase after phlebotomy. Instead of performing another phlebotomy, we...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2022/5018388 |
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| author | Rushad Machhi Ashley M. Cunningham Kenneth Hennrick Karen A. Schaser Eliot C. Williams William Nicholas Rose |
| author_facet | Rushad Machhi Ashley M. Cunningham Kenneth Hennrick Karen A. Schaser Eliot C. Williams William Nicholas Rose |
| author_sort | Rushad Machhi |
| collection | DOAJ |
| description | We report a patient with hereditary erythrocytosis who underwent a therapeutic phlebotomy and had a post-phlebotomy hematocrit that was higher than the pre-phlebotomy hematocrit. We could not discern a reason for this hematocrit increase after phlebotomy. Instead of performing another phlebotomy, we performed an automated red cell depletion via an apheresis instrument. This procedure is essentially a red cell exchange, but 5% albumin is used as the replacement fluid instead of red blood cells. The patient’s hematocrit decreased from 80% to 39% after three consecutive daily red cell depletion procedures. We share our experience to report the unusual finding of a patient’s hematocrit that increased with phlebotomy and to raise awareness of the red cell depletion procedure. |
| format | Article |
| id | doaj-art-e76e0bad7f2e4e8bb3cbd8d9c15d885a |
| institution | Kabale University |
| issn | 2090-6579 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-e76e0bad7f2e4e8bb3cbd8d9c15d885a2025-08-20T03:26:10ZengWileyCase Reports in Hematology2090-65792022-01-01202210.1155/2022/5018388Unexplained Hematocrit Increase after Therapeutic Phlebotomy in a Patient with Marked ErythrocytosisRushad Machhi0Ashley M. Cunningham1Kenneth Hennrick2Karen A. Schaser3Eliot C. Williams4William Nicholas Rose5Department of Pathology and Laboratory MedicineDepartment of Pathology and Laboratory MedicineDepartment of Pathology and Laboratory MedicineDepartment of Pathology and Laboratory MedicineDepartment of Pathology and Laboratory MedicineDepartment of Pathology and Laboratory MedicineWe report a patient with hereditary erythrocytosis who underwent a therapeutic phlebotomy and had a post-phlebotomy hematocrit that was higher than the pre-phlebotomy hematocrit. We could not discern a reason for this hematocrit increase after phlebotomy. Instead of performing another phlebotomy, we performed an automated red cell depletion via an apheresis instrument. This procedure is essentially a red cell exchange, but 5% albumin is used as the replacement fluid instead of red blood cells. The patient’s hematocrit decreased from 80% to 39% after three consecutive daily red cell depletion procedures. We share our experience to report the unusual finding of a patient’s hematocrit that increased with phlebotomy and to raise awareness of the red cell depletion procedure.http://dx.doi.org/10.1155/2022/5018388 |
| spellingShingle | Rushad Machhi Ashley M. Cunningham Kenneth Hennrick Karen A. Schaser Eliot C. Williams William Nicholas Rose Unexplained Hematocrit Increase after Therapeutic Phlebotomy in a Patient with Marked Erythrocytosis Case Reports in Hematology |
| title | Unexplained Hematocrit Increase after Therapeutic Phlebotomy in a Patient with Marked Erythrocytosis |
| title_full | Unexplained Hematocrit Increase after Therapeutic Phlebotomy in a Patient with Marked Erythrocytosis |
| title_fullStr | Unexplained Hematocrit Increase after Therapeutic Phlebotomy in a Patient with Marked Erythrocytosis |
| title_full_unstemmed | Unexplained Hematocrit Increase after Therapeutic Phlebotomy in a Patient with Marked Erythrocytosis |
| title_short | Unexplained Hematocrit Increase after Therapeutic Phlebotomy in a Patient with Marked Erythrocytosis |
| title_sort | unexplained hematocrit increase after therapeutic phlebotomy in a patient with marked erythrocytosis |
| url | http://dx.doi.org/10.1155/2022/5018388 |
| work_keys_str_mv | AT rushadmachhi unexplainedhematocritincreaseaftertherapeuticphlebotomyinapatientwithmarkederythrocytosis AT ashleymcunningham unexplainedhematocritincreaseaftertherapeuticphlebotomyinapatientwithmarkederythrocytosis AT kennethhennrick unexplainedhematocritincreaseaftertherapeuticphlebotomyinapatientwithmarkederythrocytosis AT karenaschaser unexplainedhematocritincreaseaftertherapeuticphlebotomyinapatientwithmarkederythrocytosis AT eliotcwilliams unexplainedhematocritincreaseaftertherapeuticphlebotomyinapatientwithmarkederythrocytosis AT williamnicholasrose unexplainedhematocritincreaseaftertherapeuticphlebotomyinapatientwithmarkederythrocytosis |