A Reliable and Effective UPLC-MS/MS Method for the Determination of Oprozomib in Rat Plasma

A Reliable and Effective UPLC-MS/MS Method for the Determination of Oprozomib in Rat Plasma

Oprozomib, as a second-generation orally bioavailable protease inhibitor (PI), is undergoing clinical evaluation for the treatment of haematological malignancies. In relapsed refractory multiple myeloma (RRMM) patients, oprozomib has shown good efficacy as a single agent or combination therapy. In t...

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Bibliographic Details
Main Authors: Xia Li, Ya-nan Liu, En Zhang, Ren-ai Xu, Tingyong Yang, Shunbin Luo
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Journal of Analytical Methods in Chemistry
Online Access:http://dx.doi.org/10.1155/2023/3678599
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