The impact of citicoline on brain mitochondrial dysfunction induced in rats after head irradiation

The impact of citicoline on brain mitochondrial dysfunction induced in rats after head irradiation

Abstract Head irradiation is a common treatment for brain cancer; however, it can cause side effects in healthy brain tissue. This study aimed to test whether citicoline administration modulates radiation-induced brain mitochondrial dysfunction in rats. The head of the animal was exposed to 10 Gy γ-...

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Bibliographic Details
Main Authors: Nahed Abdel-Aziz, Fatma Rabia Algeda, Shereen M. Shedid
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
γ-Radiation
Citicoline
Mitochondria
Oxidative stress
Online Access:https://doi.org/10.1038/s41598-025-11098-4
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