Can amtolmetin guacil be useful in surgical practice?

Nonsteroidal anti-inflammatory drugs (NSAIDs) are one of the main classes of analgesics and indispensable component of an integrated program of pain management in anesthetic, surgical and traumatology patients. But the use of NSAIDs may be complicated by the development of a whole range of adverse r...

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Main Author: A. E. Karateev
Format: Article
Language:Russian
Published: Remedium Group LTD 2017-06-01
Series:Амбулаторная хирургия
Subjects:
Online Access:https://www.a-surgeon.ru/jour/article/view/67
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author A. E. Karateev
author_facet A. E. Karateev
author_sort A. E. Karateev
collection DOAJ
description Nonsteroidal anti-inflammatory drugs (NSAIDs) are one of the main classes of analgesics and indispensable component of an integrated program of pain management in anesthetic, surgical and traumatology patients. But the use of NSAIDs may be complicated by the development of a whole range of adverse reactions in the gastrointestinal tract (GIT), the cardiovascular system and kidneys and increase the risk of postoperative hemorrhage. Family of NSAIDs has a lot of drugs but none of them can be considered ideal in terms of efficacy and safety. Therefore, the development of a new representative of this drug group - amtolmetin guacil - is of great interest to practitioners. This drug has the characteristics of the pharmacological action defining its gastroprotective potential (primarily due to the increase in the concentration of nitric oxide in the mucosa), and the ability to greatly reduce the negative effects on the gastrointestinal tract. Although amtolmetin guaci is mainly used for the relief of pain in diseases of joints and spine (osteoarthritis, back pain, rheumatoid arthritis, etc.), it can be used for pain management in surgical patients.
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publishDate 2017-06-01
publisher Remedium Group LTD
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series Амбулаторная хирургия
spelling doaj-art-e75fc40fffcd4f57814556d4474148bc2025-08-20T03:05:30ZrusRemedium Group LTDАмбулаторная хирургия2712-87412782-25912017-06-0101-2152267Can amtolmetin guacil be useful in surgical practice?A. E. Karateev0Nasonova Research Institute of RheumatologyNonsteroidal anti-inflammatory drugs (NSAIDs) are one of the main classes of analgesics and indispensable component of an integrated program of pain management in anesthetic, surgical and traumatology patients. But the use of NSAIDs may be complicated by the development of a whole range of adverse reactions in the gastrointestinal tract (GIT), the cardiovascular system and kidneys and increase the risk of postoperative hemorrhage. Family of NSAIDs has a lot of drugs but none of them can be considered ideal in terms of efficacy and safety. Therefore, the development of a new representative of this drug group - amtolmetin guacil - is of great interest to practitioners. This drug has the characteristics of the pharmacological action defining its gastroprotective potential (primarily due to the increase in the concentration of nitric oxide in the mucosa), and the ability to greatly reduce the negative effects on the gastrointestinal tract. Although amtolmetin guaci is mainly used for the relief of pain in diseases of joints and spine (osteoarthritis, back pain, rheumatoid arthritis, etc.), it can be used for pain management in surgical patients.https://www.a-surgeon.ru/jour/article/view/67больпослеоперационное обезболиваниенпвпамтолметил гуацилнпвп-гастропатиякардиова-скулярные осложненияpainpostoperative analgesiansaidsamtolmetin guacilnsaid-gas-tropathycardiovascular complications
spellingShingle A. E. Karateev
Can amtolmetin guacil be useful in surgical practice?
Амбулаторная хирургия
боль
послеоперационное обезболивание
нпвп
амтолметил гуацил
нпвп-гастропатия
кардиова-скулярные осложнения
pain
postoperative analgesia
nsaids
amtolmetin guacil
nsaid-gas-tropathy
cardiovascular complications
title Can amtolmetin guacil be useful in surgical practice?
title_full Can amtolmetin guacil be useful in surgical practice?
title_fullStr Can amtolmetin guacil be useful in surgical practice?
title_full_unstemmed Can amtolmetin guacil be useful in surgical practice?
title_short Can amtolmetin guacil be useful in surgical practice?
title_sort can amtolmetin guacil be useful in surgical practice
topic боль
послеоперационное обезболивание
нпвп
амтолметил гуацил
нпвп-гастропатия
кардиова-скулярные осложнения
pain
postoperative analgesia
nsaids
amtolmetin guacil
nsaid-gas-tropathy
cardiovascular complications
url https://www.a-surgeon.ru/jour/article/view/67
work_keys_str_mv AT aekarateev canamtolmetinguacilbeusefulinsurgicalpractice