PENGARUH KITOSAN DARI CANGKANG UDANG TERHADAP RED BLOOD CELL, HEMOGLOBIN, DAN TROMBOSIT PADA MODEL RHEUMATOID ARTHRITIS YANG DIINDUKSI CFA

The research was conducted the effect of chitosan on rats blood alteration that induced arthtritis. In addition, the research used pre-post test group control design. than used  was divided into groups (n=6) including normal groups, positive control, negatif control, and  groups were treated by ...

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Main Authors: Suyandra Sah Putra, Endang Darmawan
Format: Article
Language:English
Published: Universitas Ahmad Dahlan 2015-11-01
Series:Pharmaciana
Subjects:
Online Access:https://journal.uad.ac.id/index.php/PHARMACIANA/article/view/2655
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author Suyandra Sah Putra
Endang Darmawan
author_facet Suyandra Sah Putra
Endang Darmawan
author_sort Suyandra Sah Putra
collection DOAJ
description The research was conducted the effect of chitosan on rats blood alteration that induced arthtritis. In addition, the research used pre-post test group control design. than used  was divided into groups (n=6) including normal groups, positive control, negatif control, and  groups were treated by  khitosan at varian 50 mg/200gBB and 100 mg/200gBB doses. Adjuvant-induced was developed using complete Freund’s Adjuvant on 1st day, than 17-47th days after treated given appropriate their groups. To evaluate did blodd counter on 0, 16th,and 47th days after treated with otomatic optic dan electronic resisten method. Than analyzed using ANOVA test and paired t-test (p<0,05). Result of the research is Chitosan 50 mg/200gBW fit to reduce of eritrocid 6,1% (p<0,05), hemoglobin 7,77% (p<0,05) and PLCR 35,29% (p<0,05), meanwhile of Chitosan 100 mg/200gBW fit to reduce of trombocyte 40,49% (p>0,05) and PLCR 35,66% (p<0,05). In additional research, khitosan 50 mg/200gBW fit to complete blood of the rheumatoid arthritic mouse well.
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series Pharmaciana
spelling doaj-art-e75f96b0ecc04dd8b7a0482c236d010f2025-08-20T02:40:21ZengUniversitas Ahmad DahlanPharmaciana2088-45592477-02562015-11-015210.12928/pharmaciana.v5i2.2655PENGARUH KITOSAN DARI CANGKANG UDANG TERHADAP RED BLOOD CELL, HEMOGLOBIN, DAN TROMBOSIT PADA MODEL RHEUMATOID ARTHRITIS YANG DIINDUKSI CFASuyandra Sah PutraEndang Darmawan The research was conducted the effect of chitosan on rats blood alteration that induced arthtritis. In addition, the research used pre-post test group control design. than used  was divided into groups (n=6) including normal groups, positive control, negatif control, and  groups were treated by  khitosan at varian 50 mg/200gBB and 100 mg/200gBB doses. Adjuvant-induced was developed using complete Freund’s Adjuvant on 1st day, than 17-47th days after treated given appropriate their groups. To evaluate did blodd counter on 0, 16th,and 47th days after treated with otomatic optic dan electronic resisten method. Than analyzed using ANOVA test and paired t-test (p<0,05). Result of the research is Chitosan 50 mg/200gBW fit to reduce of eritrocid 6,1% (p<0,05), hemoglobin 7,77% (p<0,05) and PLCR 35,29% (p<0,05), meanwhile of Chitosan 100 mg/200gBW fit to reduce of trombocyte 40,49% (p>0,05) and PLCR 35,66% (p<0,05). In additional research, khitosan 50 mg/200gBW fit to complete blood of the rheumatoid arthritic mouse well. https://journal.uad.ac.id/index.php/PHARMACIANA/article/view/2655eggshellshrimparthriticCFA
spellingShingle Suyandra Sah Putra
Endang Darmawan
PENGARUH KITOSAN DARI CANGKANG UDANG TERHADAP RED BLOOD CELL, HEMOGLOBIN, DAN TROMBOSIT PADA MODEL RHEUMATOID ARTHRITIS YANG DIINDUKSI CFA
Pharmaciana
eggshell
shrimp
arthritic
CFA
title PENGARUH KITOSAN DARI CANGKANG UDANG TERHADAP RED BLOOD CELL, HEMOGLOBIN, DAN TROMBOSIT PADA MODEL RHEUMATOID ARTHRITIS YANG DIINDUKSI CFA
title_full PENGARUH KITOSAN DARI CANGKANG UDANG TERHADAP RED BLOOD CELL, HEMOGLOBIN, DAN TROMBOSIT PADA MODEL RHEUMATOID ARTHRITIS YANG DIINDUKSI CFA
title_fullStr PENGARUH KITOSAN DARI CANGKANG UDANG TERHADAP RED BLOOD CELL, HEMOGLOBIN, DAN TROMBOSIT PADA MODEL RHEUMATOID ARTHRITIS YANG DIINDUKSI CFA
title_full_unstemmed PENGARUH KITOSAN DARI CANGKANG UDANG TERHADAP RED BLOOD CELL, HEMOGLOBIN, DAN TROMBOSIT PADA MODEL RHEUMATOID ARTHRITIS YANG DIINDUKSI CFA
title_short PENGARUH KITOSAN DARI CANGKANG UDANG TERHADAP RED BLOOD CELL, HEMOGLOBIN, DAN TROMBOSIT PADA MODEL RHEUMATOID ARTHRITIS YANG DIINDUKSI CFA
title_sort pengaruh kitosan dari cangkang udang terhadap red blood cell hemoglobin dan trombosit pada model rheumatoid arthritis yang diinduksi cfa
topic eggshell
shrimp
arthritic
CFA
url https://journal.uad.ac.id/index.php/PHARMACIANA/article/view/2655
work_keys_str_mv AT suyandrasahputra pengaruhkitosandaricangkangudangterhadapredbloodcellhemoglobindantrombositpadamodelrheumatoidarthritisyangdiinduksicfa
AT endangdarmawan pengaruhkitosandaricangkangudangterhadapredbloodcellhemoglobindantrombositpadamodelrheumatoidarthritisyangdiinduksicfa