Opioid-Induced Constipation: Pathophysiology, Clinical Consequences, and Management
Although opioids offer potent analgesia for severe acute and chronic noncancer pain, adverse gastrointestinal effects potentially undermine their clinical utility. In particular, between 40% and 95% of patients develop opioid-induced constipation (OIC). Therefore, there is a consensus that patients...
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| Main Authors: | Lalit Kumar, Chris Barker, Anton Emmanuel |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2014-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2014/141737 |
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