Heterostructured Zn-2MI@V-COF-1@MWCNTs based electrochemical sensor for the sensitive simultaneous detection of ethyl paraben, diclofenac and epinephrine
Rational designing of practical and cost-effective electrochemical sensor with simultaneous sensing of ethyl paraben (EPB), diclofenac (DIC), and epinephrine (EPN) remains a challenging aspect. With a motive to solve this concern, a low-cost screen printed electrodes (SPCE) sensor with a novel hybri...
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Elsevier
2025-12-01
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| Series: | Talanta Open |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666831925000906 |
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| author | Antonia Trisha Zac R Yao-An Tsai Chih-Ling Yeh Hui-Ling Lee |
| author_facet | Antonia Trisha Zac R Yao-An Tsai Chih-Ling Yeh Hui-Ling Lee |
| author_sort | Antonia Trisha Zac R |
| collection | DOAJ |
| description | Rational designing of practical and cost-effective electrochemical sensor with simultaneous sensing of ethyl paraben (EPB), diclofenac (DIC), and epinephrine (EPN) remains a challenging aspect. With a motive to solve this concern, a low-cost screen printed electrodes (SPCE) sensor with a novel hybrid Zn-2MI@V-COF-1@MWCNTs modifications was put forward. In this work, an octahedral imidazole based metal organic frameworks (Zn-2MI) is combined with a two-dimensional vinylene based covalent organic frameworks (V-COF-1) to form (Zn-MOF@V-COF-1) through a simple room temperature synthesis. This hybrid is further integrated with multi-walled carbon nanotubes (MWCNTs) for enhanced analyte detection. The structural and crystalline nature of the hybrid materials was analysed using PXRD, SEM, and TEM. The material exhibits ideal porosity and a large electroactive area with multiple adsorption sites, resulting in effective, sensitive detection towards EPN, DIC, and EPB. The sensor achieves low detection limits of 0.05 µM for DIC and EPN and 0.5 µM for EPB. Real samples analysis including chili powder, liquid sweetener and energy drink are conducted using differential pulse voltammetry using satisfactory results ranging recovery rates from 81.54 to 105.8 %. These excellent performance outcomes, attributes to the synergistic effect and the presence of multiple active sites elucidates that novel Zn-2MI@V-COF-1@MWCNTs/SPCE are reliable sensors that offers quick screening, cost effective, sensitive, and allow simultaneous detection of harmful analytes in complex matrices. |
| format | Article |
| id | doaj-art-e75d371642734a18b429365efc35dda0 |
| institution | OA Journals |
| issn | 2666-8319 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Talanta Open |
| spelling | doaj-art-e75d371642734a18b429365efc35dda02025-08-20T02:17:09ZengElsevierTalanta Open2666-83192025-12-011210048810.1016/j.talo.2025.100488Heterostructured Zn-2MI@V-COF-1@MWCNTs based electrochemical sensor for the sensitive simultaneous detection of ethyl paraben, diclofenac and epinephrineAntonia Trisha Zac R0Yao-An Tsai1Chih-Ling Yeh2Hui-Ling Lee3Department of Chemistry, Fu Jen Catholic University, 510 Zhongzheng Road Xinzhuang District, New Taipei City, 24205 TaiwanDepartment of Chemistry, Fu Jen Catholic University, 510 Zhongzheng Road Xinzhuang District, New Taipei City, 24205 TaiwanDepartment of Chemistry, Fu Jen Catholic University, 510 Zhongzheng Road Xinzhuang District, New Taipei City, 24205 TaiwanCorresponding author.; Department of Chemistry, Fu Jen Catholic University, 510 Zhongzheng Road Xinzhuang District, New Taipei City, 24205 TaiwanRational designing of practical and cost-effective electrochemical sensor with simultaneous sensing of ethyl paraben (EPB), diclofenac (DIC), and epinephrine (EPN) remains a challenging aspect. With a motive to solve this concern, a low-cost screen printed electrodes (SPCE) sensor with a novel hybrid Zn-2MI@V-COF-1@MWCNTs modifications was put forward. In this work, an octahedral imidazole based metal organic frameworks (Zn-2MI) is combined with a two-dimensional vinylene based covalent organic frameworks (V-COF-1) to form (Zn-MOF@V-COF-1) through a simple room temperature synthesis. This hybrid is further integrated with multi-walled carbon nanotubes (MWCNTs) for enhanced analyte detection. The structural and crystalline nature of the hybrid materials was analysed using PXRD, SEM, and TEM. The material exhibits ideal porosity and a large electroactive area with multiple adsorption sites, resulting in effective, sensitive detection towards EPN, DIC, and EPB. The sensor achieves low detection limits of 0.05 µM for DIC and EPN and 0.5 µM for EPB. Real samples analysis including chili powder, liquid sweetener and energy drink are conducted using differential pulse voltammetry using satisfactory results ranging recovery rates from 81.54 to 105.8 %. These excellent performance outcomes, attributes to the synergistic effect and the presence of multiple active sites elucidates that novel Zn-2MI@V-COF-1@MWCNTs/SPCE are reliable sensors that offers quick screening, cost effective, sensitive, and allow simultaneous detection of harmful analytes in complex matrices.http://www.sciencedirect.com/science/article/pii/S2666831925000906DiclofenacElectrochemical sensorEpinephrineEthyl parabenHybrid materialMOF@COF |
| spellingShingle | Antonia Trisha Zac R Yao-An Tsai Chih-Ling Yeh Hui-Ling Lee Heterostructured Zn-2MI@V-COF-1@MWCNTs based electrochemical sensor for the sensitive simultaneous detection of ethyl paraben, diclofenac and epinephrine Talanta Open Diclofenac Electrochemical sensor Epinephrine Ethyl paraben Hybrid material MOF@COF |
| title | Heterostructured Zn-2MI@V-COF-1@MWCNTs based electrochemical sensor for the sensitive simultaneous detection of ethyl paraben, diclofenac and epinephrine |
| title_full | Heterostructured Zn-2MI@V-COF-1@MWCNTs based electrochemical sensor for the sensitive simultaneous detection of ethyl paraben, diclofenac and epinephrine |
| title_fullStr | Heterostructured Zn-2MI@V-COF-1@MWCNTs based electrochemical sensor for the sensitive simultaneous detection of ethyl paraben, diclofenac and epinephrine |
| title_full_unstemmed | Heterostructured Zn-2MI@V-COF-1@MWCNTs based electrochemical sensor for the sensitive simultaneous detection of ethyl paraben, diclofenac and epinephrine |
| title_short | Heterostructured Zn-2MI@V-COF-1@MWCNTs based electrochemical sensor for the sensitive simultaneous detection of ethyl paraben, diclofenac and epinephrine |
| title_sort | heterostructured zn 2mi v cof 1 mwcnts based electrochemical sensor for the sensitive simultaneous detection of ethyl paraben diclofenac and epinephrine |
| topic | Diclofenac Electrochemical sensor Epinephrine Ethyl paraben Hybrid material MOF@COF |
| url | http://www.sciencedirect.com/science/article/pii/S2666831925000906 |
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