Unmasking tuberculous arthritis in a prosthetic joint: Diagnostic and therapeutic challenges
An 85-year-old woman with a history of total knee replacements for osteoarthritis in the past, presented with left knee swelling and pain that persisted for 14 months. An initial diagnosis of synovial cyst was made, and she underwent multiple aspirations and symptomatic treatments without improvemen...
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| Language: | English |
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Elsevier
2025-01-01
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| Series: | IDCases |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214250924002105 |
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| author | Asbah Rahman Aastha Randhawa Yu Shia Lin |
| author_facet | Asbah Rahman Aastha Randhawa Yu Shia Lin |
| author_sort | Asbah Rahman |
| collection | DOAJ |
| description | An 85-year-old woman with a history of total knee replacements for osteoarthritis in the past, presented with left knee swelling and pain that persisted for 14 months. An initial diagnosis of synovial cyst was made, and she underwent multiple aspirations and symptomatic treatments without improvement. Repeat arthrocentesis showed a WBC of 56,000/μL with 61 % neutrophils and 34 % lymphocytes. Synovial fluid bacterial and fungal cultures were negative. The acid-fast bacilli (AFB) culture revealed the Mycobacterium tuberculosis complex and was confirmed by matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) Mass Spectrometry. This case highlights the challenges of diagnosing tuberculous prosthetic joint infection in an elderly individual with knee pain. |
| format | Article |
| id | doaj-art-e75c7a9d13d74340b349ee67e4a23279 |
| institution | DOAJ |
| issn | 2214-2509 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | IDCases |
| spelling | doaj-art-e75c7a9d13d74340b349ee67e4a232792025-08-20T02:52:56ZengElsevierIDCases2214-25092025-01-0139e0213410.1016/j.idcr.2024.e02134Unmasking tuberculous arthritis in a prosthetic joint: Diagnostic and therapeutic challengesAsbah Rahman0Aastha Randhawa1Yu Shia Lin2Correspondence to: Maimonides Medical Center, 4802 10th avenue, Brooklyn, NY 11219, USA.; Maimonides Medical Center, Brooklyn, NY, USAMaimonides Medical Center, Brooklyn, NY, USAMaimonides Medical Center, Brooklyn, NY, USAAn 85-year-old woman with a history of total knee replacements for osteoarthritis in the past, presented with left knee swelling and pain that persisted for 14 months. An initial diagnosis of synovial cyst was made, and she underwent multiple aspirations and symptomatic treatments without improvement. Repeat arthrocentesis showed a WBC of 56,000/μL with 61 % neutrophils and 34 % lymphocytes. Synovial fluid bacterial and fungal cultures were negative. The acid-fast bacilli (AFB) culture revealed the Mycobacterium tuberculosis complex and was confirmed by matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) Mass Spectrometry. This case highlights the challenges of diagnosing tuberculous prosthetic joint infection in an elderly individual with knee pain.http://www.sciencedirect.com/science/article/pii/S2214250924002105Mycobacterium tuberculosisProsthetic joint |
| spellingShingle | Asbah Rahman Aastha Randhawa Yu Shia Lin Unmasking tuberculous arthritis in a prosthetic joint: Diagnostic and therapeutic challenges IDCases Mycobacterium tuberculosis Prosthetic joint |
| title | Unmasking tuberculous arthritis in a prosthetic joint: Diagnostic and therapeutic challenges |
| title_full | Unmasking tuberculous arthritis in a prosthetic joint: Diagnostic and therapeutic challenges |
| title_fullStr | Unmasking tuberculous arthritis in a prosthetic joint: Diagnostic and therapeutic challenges |
| title_full_unstemmed | Unmasking tuberculous arthritis in a prosthetic joint: Diagnostic and therapeutic challenges |
| title_short | Unmasking tuberculous arthritis in a prosthetic joint: Diagnostic and therapeutic challenges |
| title_sort | unmasking tuberculous arthritis in a prosthetic joint diagnostic and therapeutic challenges |
| topic | Mycobacterium tuberculosis Prosthetic joint |
| url | http://www.sciencedirect.com/science/article/pii/S2214250924002105 |
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