CLINICAL AND HISTOPATHOLOGICAL INVESTIGATION OF IVERMECTIN TOXICITY IN PIGEONS

The aim of this study was to investigate the clinical signs and histopathological changes of acute toxicity of ivermectin in the centeral and peripheral nervous system liver, kidney, pancreas and heart of pigeons after s/c injection with ivermectin .Eighteen bird were divided into three equal grou...

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Main Author: Waleed M. S
Format: Article
Language:English
Published: College of Veterinary Medicine, University of Basrah, Iraq 2010-06-01
Series:Basrah Journal of Veterinary Research
Subjects:
Online Access:https://bjvr.uobasrah.edu.iq/article_55132_1ecc302a97dadb3e5d6192675dd99796.pdf
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author Waleed M. S
author_facet Waleed M. S
author_sort Waleed M. S
collection DOAJ
description The aim of this study was to investigate the clinical signs and histopathological changes of acute toxicity of ivermectin in the centeral and peripheral nervous system liver, kidney, pancreas and heart of pigeons after s/c injection with ivermectin .Eighteen bird were divided into three equal groups.Group A were injected with 8mg,group B were injected with 10 mg and group C served as control group.The results showed markedy reduced of water and food consumption ,somnolence and death of treated pigeons.Nervous signs were restlessness, ataxia, un steady gait, tremor and recumbent. The histopathological changes included degeneration of nerve fibers of spinal cord and sciatic nerve .Degeneration , necrosis and vacuolation were noticed in liver, kidney and heart,as wll as proliferation of bile duct was also seen in liver.
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spelling doaj-art-e754e2da54de4f0f85fcce4800eee5c42025-08-20T03:49:45ZengCollege of Veterinary Medicine, University of Basrah, IraqBasrah Journal of Veterinary Research1813-84972410-84562010-06-019113014010.33762/bvetr.2010.5513255132CLINICAL AND HISTOPATHOLOGICAL INVESTIGATION OF IVERMECTIN TOXICITY IN PIGEONSWaleed M. SThe aim of this study was to investigate the clinical signs and histopathological changes of acute toxicity of ivermectin in the centeral and peripheral nervous system liver, kidney, pancreas and heart of pigeons after s/c injection with ivermectin .Eighteen bird were divided into three equal groups.Group A were injected with 8mg,group B were injected with 10 mg and group C served as control group.The results showed markedy reduced of water and food consumption ,somnolence and death of treated pigeons.Nervous signs were restlessness, ataxia, un steady gait, tremor and recumbent. The histopathological changes included degeneration of nerve fibers of spinal cord and sciatic nerve .Degeneration , necrosis and vacuolation were noticed in liver, kidney and heart,as wll as proliferation of bile duct was also seen in liver.https://bjvr.uobasrah.edu.iq/article_55132_1ecc302a97dadb3e5d6192675dd99796.pdfliverkidneyivermectin
spellingShingle Waleed M. S
CLINICAL AND HISTOPATHOLOGICAL INVESTIGATION OF IVERMECTIN TOXICITY IN PIGEONS
Basrah Journal of Veterinary Research
liver
kidney
ivermectin
title CLINICAL AND HISTOPATHOLOGICAL INVESTIGATION OF IVERMECTIN TOXICITY IN PIGEONS
title_full CLINICAL AND HISTOPATHOLOGICAL INVESTIGATION OF IVERMECTIN TOXICITY IN PIGEONS
title_fullStr CLINICAL AND HISTOPATHOLOGICAL INVESTIGATION OF IVERMECTIN TOXICITY IN PIGEONS
title_full_unstemmed CLINICAL AND HISTOPATHOLOGICAL INVESTIGATION OF IVERMECTIN TOXICITY IN PIGEONS
title_short CLINICAL AND HISTOPATHOLOGICAL INVESTIGATION OF IVERMECTIN TOXICITY IN PIGEONS
title_sort clinical and histopathological investigation of ivermectin toxicity in pigeons
topic liver
kidney
ivermectin
url https://bjvr.uobasrah.edu.iq/article_55132_1ecc302a97dadb3e5d6192675dd99796.pdf
work_keys_str_mv AT waleedms clinicalandhistopathologicalinvestigationofivermectintoxicityinpigeons