Therapeutic management of marwari mares suffering from bacterial endometritis vis-à-vis antimicrobial sensitivity
Inappropriate use of antibiotics to treat infectious endometritis in mares can lead to increased antimicrobial resistance (AMR) and, ultimately, hinder the success of achieving pregnancy. This study aims to investigate the diagnosis and treatment of infectious endometritis in sub-fertile Marwari ma...
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Indian Council of Agricultural Research
2025-06-01
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| Series: | Indian Journal of Animal Sciences |
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| Online Access: | https://epubs.icar.org.in/index.php/IJAnS/article/view/154191 |
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| author | TARUNKUMAR VIRABHAI SUTARIA RAVJIBHAI KARSHANBHAI CHAUDHARI BHAVESH I PRAJAPATI PRAJWALITA TARUNKUMAR SUTARIA CHANDRAKANT FULJIBHAI CHAUDHARI |
| author_facet | TARUNKUMAR VIRABHAI SUTARIA RAVJIBHAI KARSHANBHAI CHAUDHARI BHAVESH I PRAJAPATI PRAJWALITA TARUNKUMAR SUTARIA CHANDRAKANT FULJIBHAI CHAUDHARI |
| author_sort | TARUNKUMAR VIRABHAI SUTARIA |
| collection | DOAJ |
| description |
Inappropriate use of antibiotics to treat infectious endometritis in mares can lead to increased antimicrobial resistance (AMR) and, ultimately, hinder the success of achieving pregnancy. This study aims to investigate the diagnosis and treatment of infectious endometritis in sub-fertile Marwari mares. The mares with a reproductive history of either failure of conception upon repeated covering or failure to exhibit estrus were investigated through trans-rectal real-time B-mode ultrasonography for intra uterine fluid-IUF, endometrial cytology-EC and bacteriology. The 61 mares (repeat breeder-50, anoestrus-9 and silent estrus-2) with bacterial uterine infection were subjected to pre-breeding treatment which comprised of sensitive antibiotics (3 g Chloramphenicol/200mg Gentamicin/3 g Ampicillin Sulbactum diluted in 50ml normal saline, intrauterine), ecbolic (25IU i/m, Inj. Oxytocin), and anti- inflammatory drugs (500mg PO, Bol. Tolfenamic Acid, bid) for three days during estrus. The mares were naturally covered by proven stallion, and pregnancy was confirmed by transrectal ultrasound examination on Day 30 post mating. The results revealed that 62.88% of mares had bacterial uterine infections and 69 isolates, with the highest frequency of E. coli (36.23%) and Staphylococcus spp. (30.43%). The chi-square analysis revealed a significant association of uterine infection with IUF and EC. The study further identified chloramphenicol and gentamicin were the most sensitive antibiotics against the bacterial isolates. The pre-breeding therapeutic management of mares resulted in a 54.01% overall pregnancy rate (48.00, 77.78 and 100.00% in RB, anoestrus and silent estrus mares, respectively). The study’s findings indicate that bacterial infections are present not only in repeat breeder mares but also in mares experiencing anestrus and silent estrus. This finding highlights the widespread prevalence of bacterial infections among different types of sub-fertile mares, emphasizing the necessity for comprehensive management strategies to tackle this issue. This study highlights the importance of pre-breeding bacterial investigation and treatment to improve fertility and minimize rise of AMR in equine industry.
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| format | Article |
| id | doaj-art-e75298fb0a3e4c72a39d4e291bd7494d |
| institution | DOAJ |
| issn | 0367-8318 2394-3327 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Indian Council of Agricultural Research |
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| series | Indian Journal of Animal Sciences |
| spelling | doaj-art-e75298fb0a3e4c72a39d4e291bd7494d2025-08-20T03:12:26ZengIndian Council of Agricultural ResearchIndian Journal of Animal Sciences0367-83182394-33272025-06-0195310.56093/ijans.v95i4.154191Therapeutic management of marwari mares suffering from bacterial endometritis vis-à-vis antimicrobial sensitivityTARUNKUMAR VIRABHAI SUTARIA0RAVJIBHAI KARSHANBHAI CHAUDHARI1BHAVESH I PRAJAPATI2PRAJWALITA TARUNKUMAR SUTARIA3CHANDRAKANT FULJIBHAI CHAUDHARI4Kamdhenu University, Sardarkrushinagar-385 006, Gujarat, IndiaKamdhenu University, Sardarkrushinagar-385 006, Gujarat, IndiaKamdhenu University, Sardarkrushinagar-385 006, Gujarat, IndiaKamdhenu University, Sardarkrushinagar-385 006, Gujarat, IndiaKamdhenu University, Sardarkrushinagar-385 006, Gujarat, India Inappropriate use of antibiotics to treat infectious endometritis in mares can lead to increased antimicrobial resistance (AMR) and, ultimately, hinder the success of achieving pregnancy. This study aims to investigate the diagnosis and treatment of infectious endometritis in sub-fertile Marwari mares. The mares with a reproductive history of either failure of conception upon repeated covering or failure to exhibit estrus were investigated through trans-rectal real-time B-mode ultrasonography for intra uterine fluid-IUF, endometrial cytology-EC and bacteriology. The 61 mares (repeat breeder-50, anoestrus-9 and silent estrus-2) with bacterial uterine infection were subjected to pre-breeding treatment which comprised of sensitive antibiotics (3 g Chloramphenicol/200mg Gentamicin/3 g Ampicillin Sulbactum diluted in 50ml normal saline, intrauterine), ecbolic (25IU i/m, Inj. Oxytocin), and anti- inflammatory drugs (500mg PO, Bol. Tolfenamic Acid, bid) for three days during estrus. The mares were naturally covered by proven stallion, and pregnancy was confirmed by transrectal ultrasound examination on Day 30 post mating. The results revealed that 62.88% of mares had bacterial uterine infections and 69 isolates, with the highest frequency of E. coli (36.23%) and Staphylococcus spp. (30.43%). The chi-square analysis revealed a significant association of uterine infection with IUF and EC. The study further identified chloramphenicol and gentamicin were the most sensitive antibiotics against the bacterial isolates. The pre-breeding therapeutic management of mares resulted in a 54.01% overall pregnancy rate (48.00, 77.78 and 100.00% in RB, anoestrus and silent estrus mares, respectively). The study’s findings indicate that bacterial infections are present not only in repeat breeder mares but also in mares experiencing anestrus and silent estrus. This finding highlights the widespread prevalence of bacterial infections among different types of sub-fertile mares, emphasizing the necessity for comprehensive management strategies to tackle this issue. This study highlights the importance of pre-breeding bacterial investigation and treatment to improve fertility and minimize rise of AMR in equine industry. https://epubs.icar.org.in/index.php/IJAnS/article/view/154191Antibiotic sensitivity, Antimicrobial resistance (AMR), Endometritis, Marwari Mare, Pregnancy |
| spellingShingle | TARUNKUMAR VIRABHAI SUTARIA RAVJIBHAI KARSHANBHAI CHAUDHARI BHAVESH I PRAJAPATI PRAJWALITA TARUNKUMAR SUTARIA CHANDRAKANT FULJIBHAI CHAUDHARI Therapeutic management of marwari mares suffering from bacterial endometritis vis-à-vis antimicrobial sensitivity Indian Journal of Animal Sciences Antibiotic sensitivity, Antimicrobial resistance (AMR), Endometritis, Marwari Mare, Pregnancy |
| title | Therapeutic management of marwari mares suffering from bacterial endometritis vis-à-vis antimicrobial sensitivity |
| title_full | Therapeutic management of marwari mares suffering from bacterial endometritis vis-à-vis antimicrobial sensitivity |
| title_fullStr | Therapeutic management of marwari mares suffering from bacterial endometritis vis-à-vis antimicrobial sensitivity |
| title_full_unstemmed | Therapeutic management of marwari mares suffering from bacterial endometritis vis-à-vis antimicrobial sensitivity |
| title_short | Therapeutic management of marwari mares suffering from bacterial endometritis vis-à-vis antimicrobial sensitivity |
| title_sort | therapeutic management of marwari mares suffering from bacterial endometritis vis a vis antimicrobial sensitivity |
| topic | Antibiotic sensitivity, Antimicrobial resistance (AMR), Endometritis, Marwari Mare, Pregnancy |
| url | https://epubs.icar.org.in/index.php/IJAnS/article/view/154191 |
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