Targeting LINC00707 by vitamin D3 attenuates nitrogen mustard-caused dermal toxicity through inhibiting ferroptosis

Targeting LINC00707 by vitamin D3 attenuates nitrogen mustard-caused dermal toxicity through inhibiting ferroptosis

Nitrogen mustard (NM) causes severe skin injury that is lack of effective and targeted therapies. Vitamin D3 (VD3) emerges as a promising treatment option for NM-caused dermal toxicity; however, the underlying mechanisms are currently unclear. Herein, we identified that NM markedly promoted ferropto...

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Bibliographic Details
Main Authors: Xunhu Dong, Ying He, Xiaofeng Hu, Jie Wu, Feng Ye, Xiaogang Wang, Yuanpeng Zhao, Guorong Dan, Jiqing Zhao, He Tang, Xiaolu Lu, Yan Sai, Zhongmin Zou, Mingliang Chen
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Redox Biology
Subjects:
Vitamin D3
Nitrogen mustard
LINC00707
Nrf2
Ferroptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231725001417
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