Refining early detection of Marburg Virus Disease (MVD) in Rwanda: Leveraging predictive symptom clusters to enhance case definitions

Refining early detection of Marburg Virus Disease (MVD) in Rwanda: Leveraging predictive symptom clusters to enhance case definitions

Background: Marburg Virus Disease (MVD) poses a significant global health risk due to its high case fatality rates (24%-88%) and the diagnostic challenges posed by its nonspecific early symptoms, which overlap with other febrile illnesses like malaria. This study analyzed symptom patterns from the 2...

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Bibliographic Details
Main Authors: Olivier Nsekuye, Frederick Ntabana, Hugues Valois Mucunguzi, Ziad El-Khatib, Eric Remera, Lyndah Makayotto, Menelas Nkeshimana, David Turatsinze, Frederic Ntirenganya, Semakula Muhammed, Athanase Rukundo, Brian Chirombo, Richard Muvunyi, Claude Mambo Muvunyi, Pacifique Nizeyimana, Yvan Butera, Sabin Nsanzimana, Edson Rwagasore
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:International Journal of Infectious Diseases
Subjects:
Marburg Virus Disease
Symptom patterns
Early detection
Machine learning
Outbreak response
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971225001250
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