Bleeding Complication of Triple Therapy of Rivaroxaban, Prasugrel, and Aspirin: A Case Report and General Discussion
Hemorrhagic side effects are the bane of oral anticoagulation. Despite careful selection of medications and close monitoring, some adverse events are unavoidable. The available literature about the risks of triple oral anticoagulation therapy versus dual antiplatelet therapy does not address all of...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Cardiology |
| Online Access: | http://dx.doi.org/10.1155/2014/293476 |
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| _version_ | 1832549828074143744 |
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| author | Dane D. Gruenebaum Ahmad Alsarah Osama Alsara Heather Laird-Fick |
| author_facet | Dane D. Gruenebaum Ahmad Alsarah Osama Alsara Heather Laird-Fick |
| author_sort | Dane D. Gruenebaum |
| collection | DOAJ |
| description | Hemorrhagic side effects are the bane of oral anticoagulation. Despite careful selection of medications and close monitoring, some adverse events are unavoidable. The available literature about the risks of triple oral anticoagulation therapy versus dual antiplatelet therapy does not address all of the medication combinations currently available. This report describes a patient with atrial fibrillation and recent stent placement who developed severe, recurrent epistaxis on aspirin, prosugrel, and rivaroxaban. We believe this is the first case report of severe bleeding with this combination, and it may help provide insights into the risk for other patients. |
| format | Article |
| id | doaj-art-e740944c4bb14294a1b7597bad64c624 |
| institution | Kabale University |
| issn | 2090-6404 2090-6412 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Cardiology |
| spelling | doaj-art-e740944c4bb14294a1b7597bad64c6242025-02-03T06:08:36ZengWileyCase Reports in Cardiology2090-64042090-64122014-01-01201410.1155/2014/293476293476Bleeding Complication of Triple Therapy of Rivaroxaban, Prasugrel, and Aspirin: A Case Report and General DiscussionDane D. Gruenebaum0Ahmad Alsarah1Osama Alsara2Heather Laird-Fick3Department of Internal Medicine, Michigan State University, B-301 Clinical Center, East Lansing, MI 48824, USADepartment of Internal Medicine, Michigan State University, B-301 Clinical Center, East Lansing, MI 48824, USADepartment of Internal Medicine, Michigan State University, B-301 Clinical Center, East Lansing, MI 48824, USADepartment of Internal Medicine, Michigan State University, B-301 Clinical Center, East Lansing, MI 48824, USAHemorrhagic side effects are the bane of oral anticoagulation. Despite careful selection of medications and close monitoring, some adverse events are unavoidable. The available literature about the risks of triple oral anticoagulation therapy versus dual antiplatelet therapy does not address all of the medication combinations currently available. This report describes a patient with atrial fibrillation and recent stent placement who developed severe, recurrent epistaxis on aspirin, prosugrel, and rivaroxaban. We believe this is the first case report of severe bleeding with this combination, and it may help provide insights into the risk for other patients.http://dx.doi.org/10.1155/2014/293476 |
| spellingShingle | Dane D. Gruenebaum Ahmad Alsarah Osama Alsara Heather Laird-Fick Bleeding Complication of Triple Therapy of Rivaroxaban, Prasugrel, and Aspirin: A Case Report and General Discussion Case Reports in Cardiology |
| title | Bleeding Complication of Triple Therapy of Rivaroxaban, Prasugrel, and Aspirin: A Case Report and General Discussion |
| title_full | Bleeding Complication of Triple Therapy of Rivaroxaban, Prasugrel, and Aspirin: A Case Report and General Discussion |
| title_fullStr | Bleeding Complication of Triple Therapy of Rivaroxaban, Prasugrel, and Aspirin: A Case Report and General Discussion |
| title_full_unstemmed | Bleeding Complication of Triple Therapy of Rivaroxaban, Prasugrel, and Aspirin: A Case Report and General Discussion |
| title_short | Bleeding Complication of Triple Therapy of Rivaroxaban, Prasugrel, and Aspirin: A Case Report and General Discussion |
| title_sort | bleeding complication of triple therapy of rivaroxaban prasugrel and aspirin a case report and general discussion |
| url | http://dx.doi.org/10.1155/2014/293476 |
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