ABSENCE OF FOVEAL DEPRESSION AND ITS ASSOCIATION WITH REFRACTIVE STATUS AND STRABISMUS IN CHILDREN WITH HISTORY OF RETINOPATHY OF PREMATURITY

Objective: To evaluate the foveal depression (FD) status on optical coherence tomography (OCT) and its relationship with strabismus, amblyopia and refractive errors in children with a history of retinopathy of prematurity (ROP).Material and Method: Medical records were reviewed for demographic data,...

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Main Authors: Nihan Aksu Ceylan, Merve Bahar, Kemal Turgay Özbilen, Zafer Cebeci, Mehmet Eren Güner, Nur Kır
Format: Article
Language:English
Published: Istanbul University Press 2023-08-01
Series:İstanbul Tıp Fakültesi Dergisi
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Online Access:https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/C4A4A739AAF348CB8D15E796B60AC835
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author Nihan Aksu Ceylan
Merve Bahar
Kemal Turgay Özbilen
Zafer Cebeci
Mehmet Eren Güner
Nur Kır
author_facet Nihan Aksu Ceylan
Merve Bahar
Kemal Turgay Özbilen
Zafer Cebeci
Mehmet Eren Güner
Nur Kır
author_sort Nihan Aksu Ceylan
collection DOAJ
description Objective: To evaluate the foveal depression (FD) status on optical coherence tomography (OCT) and its relationship with strabismus, amblyopia and refractive errors in children with a history of retinopathy of prematurity (ROP).Material and Method: Medical records were reviewed for demographic data, ocular and medical history, systemic disorders, ophthalmologic and OCT findings. Patients were categorized into two groups according to foveal depression status on OCT: absence of FD (Non-FD Group) and presence of FD (FD Group). Demographic data, refractive errors (RE), strabismus, amblyopia and anisometropia were compared between the groups.Result: Mean age of the patients was 11.1±2.7 years in the Non-FD group and 10.1±2.9 years in the FD group (p=0.136). Mean gestastional age (GA) at birth and birth weight (BW) of the Non-FD group (28.8±2.7 weeks, 1269.1±455.5 grams) were significantly lower than those of the FD group (30.8±2.1weeks, 1530.8±415.2 grams) (p=0.002 and p=0.02, respectively). Although there was no significant difference between the groups in the mean spherical equivalent (SE) RE (-1.19± 4.86D in the Non-FD group and 0.77±4.08D in the FD group, p=0.09), the distribution of SE refractive errors was significantly different (p=0.001). 54.5% of patients in the Non-FD group had myopia and 72% of the patients in the FD group had hypermetropia. Mild myopia was significantly more in the Non-FD group and mild hypermetropia was significantly more in the FD group (p<0.05 for both). Astigmatism equal or greater than 1.50D was detected in 56.5% of the Non-FD group and 36% of the FD group (p>0.05). There was no significant difference between the groups in the incidence of strabismus, amblyopia and anisometropia (p>0.05).Conclusion: We detected lower GA and BW in the Non-FD group than those of the FD group. Myopia is more prevalent in patients with a history of ROP and absence of FD than in those with a normal foveal structure.
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spelling doaj-art-e740579a2bff4986b1025d1485fe33e62025-08-20T02:15:38ZengIstanbul University Pressİstanbul Tıp Fakültesi Dergisi1305-64412023-08-0186320421010.26650/IUITFD.1254425123456ABSENCE OF FOVEAL DEPRESSION AND ITS ASSOCIATION WITH REFRACTIVE STATUS AND STRABISMUS IN CHILDREN WITH HISTORY OF RETINOPATHY OF PREMATURITYNihan Aksu Ceylan0https://orcid.org/0000-0003-3724-7659Merve Bahar1https://orcid.org/0000-0002-3800-7617Kemal Turgay Özbilen2https://orcid.org/0000-0002-0234-3803Zafer Cebeci3https://orcid.org/0000-0001-5949-4082Mehmet Eren Güner4https://orcid.org/0000-0002-5335-4051Nur Kır5https://orcid.org/0000-0002-4347-0630İstanbul Üniversitesi, İstanbul, Türkiyeİstanbul Üniversitesi, İstanbul, Türkiyeİstanbul Üniversitesi, İstanbul, Türkiyeİstanbul Üniversitesi, İstanbul, Türkiyeİstanbul Üniversitesi, İstanbul, Türkiyeİstanbul Üniversitesi, İstanbul, TürkiyeObjective: To evaluate the foveal depression (FD) status on optical coherence tomography (OCT) and its relationship with strabismus, amblyopia and refractive errors in children with a history of retinopathy of prematurity (ROP).Material and Method: Medical records were reviewed for demographic data, ocular and medical history, systemic disorders, ophthalmologic and OCT findings. Patients were categorized into two groups according to foveal depression status on OCT: absence of FD (Non-FD Group) and presence of FD (FD Group). Demographic data, refractive errors (RE), strabismus, amblyopia and anisometropia were compared between the groups.Result: Mean age of the patients was 11.1±2.7 years in the Non-FD group and 10.1±2.9 years in the FD group (p=0.136). Mean gestastional age (GA) at birth and birth weight (BW) of the Non-FD group (28.8±2.7 weeks, 1269.1±455.5 grams) were significantly lower than those of the FD group (30.8±2.1weeks, 1530.8±415.2 grams) (p=0.002 and p=0.02, respectively). Although there was no significant difference between the groups in the mean spherical equivalent (SE) RE (-1.19± 4.86D in the Non-FD group and 0.77±4.08D in the FD group, p=0.09), the distribution of SE refractive errors was significantly different (p=0.001). 54.5% of patients in the Non-FD group had myopia and 72% of the patients in the FD group had hypermetropia. Mild myopia was significantly more in the Non-FD group and mild hypermetropia was significantly more in the FD group (p<0.05 for both). Astigmatism equal or greater than 1.50D was detected in 56.5% of the Non-FD group and 36% of the FD group (p>0.05). There was no significant difference between the groups in the incidence of strabismus, amblyopia and anisometropia (p>0.05).Conclusion: We detected lower GA and BW in the Non-FD group than those of the FD group. Myopia is more prevalent in patients with a history of ROP and absence of FD than in those with a normal foveal structure.https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/C4A4A739AAF348CB8D15E796B60AC835retinopathy of prematurityoptical coherence tomographymyopiaastigmatismstrabismusrefractive errors
spellingShingle Nihan Aksu Ceylan
Merve Bahar
Kemal Turgay Özbilen
Zafer Cebeci
Mehmet Eren Güner
Nur Kır
ABSENCE OF FOVEAL DEPRESSION AND ITS ASSOCIATION WITH REFRACTIVE STATUS AND STRABISMUS IN CHILDREN WITH HISTORY OF RETINOPATHY OF PREMATURITY
İstanbul Tıp Fakültesi Dergisi
retinopathy of prematurity
optical coherence tomography
myopia
astigmatism
strabismus
refractive errors
title ABSENCE OF FOVEAL DEPRESSION AND ITS ASSOCIATION WITH REFRACTIVE STATUS AND STRABISMUS IN CHILDREN WITH HISTORY OF RETINOPATHY OF PREMATURITY
title_full ABSENCE OF FOVEAL DEPRESSION AND ITS ASSOCIATION WITH REFRACTIVE STATUS AND STRABISMUS IN CHILDREN WITH HISTORY OF RETINOPATHY OF PREMATURITY
title_fullStr ABSENCE OF FOVEAL DEPRESSION AND ITS ASSOCIATION WITH REFRACTIVE STATUS AND STRABISMUS IN CHILDREN WITH HISTORY OF RETINOPATHY OF PREMATURITY
title_full_unstemmed ABSENCE OF FOVEAL DEPRESSION AND ITS ASSOCIATION WITH REFRACTIVE STATUS AND STRABISMUS IN CHILDREN WITH HISTORY OF RETINOPATHY OF PREMATURITY
title_short ABSENCE OF FOVEAL DEPRESSION AND ITS ASSOCIATION WITH REFRACTIVE STATUS AND STRABISMUS IN CHILDREN WITH HISTORY OF RETINOPATHY OF PREMATURITY
title_sort absence of foveal depression and its association with refractive status and strabismus in children with history of retinopathy of prematurity
topic retinopathy of prematurity
optical coherence tomography
myopia
astigmatism
strabismus
refractive errors
url https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/C4A4A739AAF348CB8D15E796B60AC835
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