Y‐Chromosome Genetic Characterization Supports the Establishment of Calving Centered Protected Areas for Tibetan Antelope Conservation

ABSTRACT Tibetan antelope (Pantholops hodgsonii), the flagship species of the Qinghai–Tibet Plateau, is renowned for its hardiness and resistance to low oxygen. Most of the previous studies focused on mitochondria and autosomes, with fewer studies related to the Y‐chromosome. Therefore, in this stud...

Full description

Saved in:
Bibliographic Details
Main Authors: Shuwen Wang, Jingqing Ma, Ruotong Cheng, Jingyi Li, Xun Zhang, Zhongyuan Lin, Qing Wei, Jiarui Chen
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Ecology and Evolution
Subjects:
Online Access:https://doi.org/10.1002/ece3.71897
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849224551739686912
author Shuwen Wang
Jingqing Ma
Ruotong Cheng
Jingyi Li
Xun Zhang
Zhongyuan Lin
Qing Wei
Jiarui Chen
author_facet Shuwen Wang
Jingqing Ma
Ruotong Cheng
Jingyi Li
Xun Zhang
Zhongyuan Lin
Qing Wei
Jiarui Chen
author_sort Shuwen Wang
collection DOAJ
description ABSTRACT Tibetan antelope (Pantholops hodgsonii), the flagship species of the Qinghai–Tibet Plateau, is renowned for its hardiness and resistance to low oxygen. Most of the previous studies focused on mitochondria and autosomes, with fewer studies related to the Y‐chromosome. Therefore, in this study, we analyzed the Y‐chromosome genetic diversity, population structure, and historical dynamics of Tibetan antelope populations using 26 Y‐SNP loci and 5 Y‐SSR polymorphic loci. Our results revealed a nucleotide diversity of 0.00092 ± 0.00002 and a haplotype diversity of 0.843 ± 0.029 based on 26 Y‐SNPs from 14 sequences, with a total DNA sequence length of 10,675 bp. Genotyping of 123 Tibetan antelope male samples with 5 Y‐SSR loci indicated a mean observed number of alleles of 6.600, an effective number of alleles of 4.071, Shannon's Information index of 1.215, Nei's gene diversity of 0.556, and a PIC (Polymorphism Information Content) of 0.522. The population structure analysis classified all samples into three genetic populations, showing significant genetic differentiation that dates back approximately 170,000 years. However, no corresponding relationship was found between genetic populations and their geographical distribution, suggesting population convergence among Tibetan antelope populations. We inferred that population convergence facilitated genetic mixing, so that the population was able to maintain a relatively high genetic diversity after experiencing a severe hunting crisis. Given these findings, we highlight that the current model of protected areas, which are divided into administrative areas, while offering some protection, may not be optimal for the long‐term conservation of Tibetan antelope populations. Therefore, we propose to establish a system of protected areas centered around protecting calving regions, ensuring that key breeding habitats are effectively safeguarded, while simultaneously fostering natural connections and gene flow among populations, thereby providing a safer, more suitable, and coherent living environment for the Tibetan antelope.
format Article
id doaj-art-e73a25690e9c43c69ed22d18e7e58e8f
institution Kabale University
issn 2045-7758
language English
publishDate 2025-08-01
publisher Wiley
record_format Article
series Ecology and Evolution
spelling doaj-art-e73a25690e9c43c69ed22d18e7e58e8f2025-08-25T08:12:55ZengWileyEcology and Evolution2045-77582025-08-01158n/an/a10.1002/ece3.71897Y‐Chromosome Genetic Characterization Supports the Establishment of Calving Centered Protected Areas for Tibetan Antelope ConservationShuwen Wang0Jingqing Ma1Ruotong Cheng2Jingyi Li3Xun Zhang4Zhongyuan Lin5Qing Wei6Jiarui Chen7College of eco‐Environmental Engineering Qinghai University Xining Qinghai ChinaCollege of eco‐Environmental Engineering Qinghai University Xining Qinghai ChinaCollege of eco‐Environmental Engineering Qinghai University Xining Qinghai ChinaCollege of eco‐Environmental Engineering Qinghai University Xining Qinghai ChinaCollege of eco‐Environmental Engineering Qinghai University Xining Qinghai ChinaCollege of eco‐Environmental Engineering Qinghai University Xining Qinghai ChinaCollege of eco‐Environmental Engineering Qinghai University Xining Qinghai ChinaCollege of eco‐Environmental Engineering Qinghai University Xining Qinghai ChinaABSTRACT Tibetan antelope (Pantholops hodgsonii), the flagship species of the Qinghai–Tibet Plateau, is renowned for its hardiness and resistance to low oxygen. Most of the previous studies focused on mitochondria and autosomes, with fewer studies related to the Y‐chromosome. Therefore, in this study, we analyzed the Y‐chromosome genetic diversity, population structure, and historical dynamics of Tibetan antelope populations using 26 Y‐SNP loci and 5 Y‐SSR polymorphic loci. Our results revealed a nucleotide diversity of 0.00092 ± 0.00002 and a haplotype diversity of 0.843 ± 0.029 based on 26 Y‐SNPs from 14 sequences, with a total DNA sequence length of 10,675 bp. Genotyping of 123 Tibetan antelope male samples with 5 Y‐SSR loci indicated a mean observed number of alleles of 6.600, an effective number of alleles of 4.071, Shannon's Information index of 1.215, Nei's gene diversity of 0.556, and a PIC (Polymorphism Information Content) of 0.522. The population structure analysis classified all samples into three genetic populations, showing significant genetic differentiation that dates back approximately 170,000 years. However, no corresponding relationship was found between genetic populations and their geographical distribution, suggesting population convergence among Tibetan antelope populations. We inferred that population convergence facilitated genetic mixing, so that the population was able to maintain a relatively high genetic diversity after experiencing a severe hunting crisis. Given these findings, we highlight that the current model of protected areas, which are divided into administrative areas, while offering some protection, may not be optimal for the long‐term conservation of Tibetan antelope populations. Therefore, we propose to establish a system of protected areas centered around protecting calving regions, ensuring that key breeding habitats are effectively safeguarded, while simultaneously fostering natural connections and gene flow among populations, thereby providing a safer, more suitable, and coherent living environment for the Tibetan antelope.https://doi.org/10.1002/ece3.71897population convergenceprotectTibetan antelopeY‐SNPY‐SSR
spellingShingle Shuwen Wang
Jingqing Ma
Ruotong Cheng
Jingyi Li
Xun Zhang
Zhongyuan Lin
Qing Wei
Jiarui Chen
Y‐Chromosome Genetic Characterization Supports the Establishment of Calving Centered Protected Areas for Tibetan Antelope Conservation
Ecology and Evolution
population convergence
protect
Tibetan antelope
Y‐SNP
Y‐SSR
title Y‐Chromosome Genetic Characterization Supports the Establishment of Calving Centered Protected Areas for Tibetan Antelope Conservation
title_full Y‐Chromosome Genetic Characterization Supports the Establishment of Calving Centered Protected Areas for Tibetan Antelope Conservation
title_fullStr Y‐Chromosome Genetic Characterization Supports the Establishment of Calving Centered Protected Areas for Tibetan Antelope Conservation
title_full_unstemmed Y‐Chromosome Genetic Characterization Supports the Establishment of Calving Centered Protected Areas for Tibetan Antelope Conservation
title_short Y‐Chromosome Genetic Characterization Supports the Establishment of Calving Centered Protected Areas for Tibetan Antelope Conservation
title_sort y chromosome genetic characterization supports the establishment of calving centered protected areas for tibetan antelope conservation
topic population convergence
protect
Tibetan antelope
Y‐SNP
Y‐SSR
url https://doi.org/10.1002/ece3.71897
work_keys_str_mv AT shuwenwang ychromosomegeneticcharacterizationsupportstheestablishmentofcalvingcenteredprotectedareasfortibetanantelopeconservation
AT jingqingma ychromosomegeneticcharacterizationsupportstheestablishmentofcalvingcenteredprotectedareasfortibetanantelopeconservation
AT ruotongcheng ychromosomegeneticcharacterizationsupportstheestablishmentofcalvingcenteredprotectedareasfortibetanantelopeconservation
AT jingyili ychromosomegeneticcharacterizationsupportstheestablishmentofcalvingcenteredprotectedareasfortibetanantelopeconservation
AT xunzhang ychromosomegeneticcharacterizationsupportstheestablishmentofcalvingcenteredprotectedareasfortibetanantelopeconservation
AT zhongyuanlin ychromosomegeneticcharacterizationsupportstheestablishmentofcalvingcenteredprotectedareasfortibetanantelopeconservation
AT qingwei ychromosomegeneticcharacterizationsupportstheestablishmentofcalvingcenteredprotectedareasfortibetanantelopeconservation
AT jiaruichen ychromosomegeneticcharacterizationsupportstheestablishmentofcalvingcenteredprotectedareasfortibetanantelopeconservation