Antimicrobial susceptibility of select respiratory tract pathogens in Dakar, Senegal
Background : Haemophilus influenzae, Moraxella catarrhalis, Streptococcus pyogenes, and Streptococcus pneumoniae are the most common causative agents of respiratory tract infections (RTIs). The increase in resistance to current antibacterial agents highlights the need to monitor the resistance pat...
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| Format: | Article |
| Language: | English |
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The Journal of Infection in Developing Countries
2009-10-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/20 |
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| author | Aissatou Geuye Ndiaye Cheikh Saadbou Boye Edwige Hounkponou Fatou Bintou Gueye Aida Badiane |
| author_facet | Aissatou Geuye Ndiaye Cheikh Saadbou Boye Edwige Hounkponou Fatou Bintou Gueye Aida Badiane |
| author_sort | Aissatou Geuye Ndiaye |
| collection | DOAJ |
| description |
Background : Haemophilus influenzae, Moraxella catarrhalis, Streptococcus pyogenes, and Streptococcus pneumoniae are the most common causative agents of respiratory tract infections (RTIs). The increase in resistance to current antibacterial agents highlights the need to monitor the resistance pattern of these bacterial pathogens.
Methodology: In this study, we assessed the antibacterial susceptibility of these pathogens causing respiratory tract infections in Dakar, Senegal, during 2007-2008. A total of 290 bacterial isolates (75 H. influenzae, 10 M. catarrhalis, 105 S. pneumoniae, and 100 S. pyogenes) were collected.
Results and Conclusions: All H. influenzae isolates were susceptible to amoxicillin/clavulanic acid, ofloxacin, clarithromycin, cephalosporins, and macrolides. Overall, 26.7% of H. influenzae isolates were completely resistant to ampicillin. Among the M. catarrhalis isolates, 30% were resistant to ampicillin. All the isolates of H. influenzae and M. catarrhalis that were resistant to ampicillin were beta-lactamase producing strains. Among the S. pneumoniae isolates, 33.3% isolates exhibited intermediate susceptibility to penicillin G, and one isolate was completely resistant. All five isolates that were resistant to erythromycin expressed the M phenotype. S. pyogenes exhibited high susceptibility to all other antibiotics, except tetracycline. Our study suggests that except for M. catarrhalis, all other bacterial isolates are susceptible to cephalosporins, macrolides, and fluroquinolones.
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| format | Article |
| id | doaj-art-e73a160a3eb14bb8ae61d7ad1cf9e803 |
| institution | Kabale University |
| issn | 1972-2680 |
| language | English |
| publishDate | 2009-10-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-e73a160a3eb14bb8ae61d7ad1cf9e8032025-08-20T03:48:58ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802009-10-0130910.3855/jidc.20Antimicrobial susceptibility of select respiratory tract pathogens in Dakar, SenegalAissatou Geuye Ndiaye0Cheikh Saadbou Boye1Edwige Hounkponou2Fatou Bintou Gueye3Aida Badiane4Bacteriology and Virology Laboratory, Dantec Teaching Hospital, DakarBacteriology and Virology Laboratory, Dantec Teaching Hospital, DakarBacteriology and Virology Laboratory, Dantec Teaching Hospital, DakarBacteriology and Virology Laboratory, Dantec Teaching Hospital, DakarBacteriology and Virology Laboratory, Dantec Teaching Hospital, Dakar Background : Haemophilus influenzae, Moraxella catarrhalis, Streptococcus pyogenes, and Streptococcus pneumoniae are the most common causative agents of respiratory tract infections (RTIs). The increase in resistance to current antibacterial agents highlights the need to monitor the resistance pattern of these bacterial pathogens. Methodology: In this study, we assessed the antibacterial susceptibility of these pathogens causing respiratory tract infections in Dakar, Senegal, during 2007-2008. A total of 290 bacterial isolates (75 H. influenzae, 10 M. catarrhalis, 105 S. pneumoniae, and 100 S. pyogenes) were collected. Results and Conclusions: All H. influenzae isolates were susceptible to amoxicillin/clavulanic acid, ofloxacin, clarithromycin, cephalosporins, and macrolides. Overall, 26.7% of H. influenzae isolates were completely resistant to ampicillin. Among the M. catarrhalis isolates, 30% were resistant to ampicillin. All the isolates of H. influenzae and M. catarrhalis that were resistant to ampicillin were beta-lactamase producing strains. Among the S. pneumoniae isolates, 33.3% isolates exhibited intermediate susceptibility to penicillin G, and one isolate was completely resistant. All five isolates that were resistant to erythromycin expressed the M phenotype. S. pyogenes exhibited high susceptibility to all other antibiotics, except tetracycline. Our study suggests that except for M. catarrhalis, all other bacterial isolates are susceptible to cephalosporins, macrolides, and fluroquinolones. https://jidc.org/index.php/journal/article/view/20Haemophilus influenzaeMoraxella catarrhalisStreptococcus pneumoniaeStreptococcus pyogenessusceptibility. |
| spellingShingle | Aissatou Geuye Ndiaye Cheikh Saadbou Boye Edwige Hounkponou Fatou Bintou Gueye Aida Badiane Antimicrobial susceptibility of select respiratory tract pathogens in Dakar, Senegal Journal of Infection in Developing Countries Haemophilus influenzae Moraxella catarrhalis Streptococcus pneumoniae Streptococcus pyogenes susceptibility. |
| title | Antimicrobial susceptibility of select respiratory tract pathogens in Dakar, Senegal |
| title_full | Antimicrobial susceptibility of select respiratory tract pathogens in Dakar, Senegal |
| title_fullStr | Antimicrobial susceptibility of select respiratory tract pathogens in Dakar, Senegal |
| title_full_unstemmed | Antimicrobial susceptibility of select respiratory tract pathogens in Dakar, Senegal |
| title_short | Antimicrobial susceptibility of select respiratory tract pathogens in Dakar, Senegal |
| title_sort | antimicrobial susceptibility of select respiratory tract pathogens in dakar senegal |
| topic | Haemophilus influenzae Moraxella catarrhalis Streptococcus pneumoniae Streptococcus pyogenes susceptibility. |
| url | https://jidc.org/index.php/journal/article/view/20 |
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