The Role of the Innate Immune System in the Development of Postcovid Syndrome and its Complications

To date, the problem of preserving symptoms after recovery from a new coronavirus infection is urgent in the world. This condition is called postcovid syndrome. The clinical picture of postcovid syndrome has multiple manifestations: general, respiratory, cardiovascular, gastrointestinal, skin and ot...

Full description

Saved in:
Bibliographic Details
Main Authors: V. N. Larina, E. A. Stodelova, Zh. M. Salmasi, A. N. Kazimirskij, G. V. Porjadin
Format: Article
Language:Russian
Published: SINAPS LLC 2023-08-01
Series:Архивъ внутренней медицины
Subjects:
Online Access:https://www.medarhive.ru/jour/article/view/1637
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849303276815646720
author V. N. Larina
E. A. Stodelova
Zh. M. Salmasi
A. N. Kazimirskij
G. V. Porjadin
author_facet V. N. Larina
E. A. Stodelova
Zh. M. Salmasi
A. N. Kazimirskij
G. V. Porjadin
author_sort V. N. Larina
collection DOAJ
description To date, the problem of preserving symptoms after recovery from a new coronavirus infection is urgent in the world. This condition is called postcovid syndrome. The clinical picture of postcovid syndrome has multiple manifestations: general, respiratory, cardiovascular, gastrointestinal, skin and other symptoms. At the moment, there are no laboratory criteria for the diagnosis of this condition, but the great role of neutrophils in the development of both acute disease and postcovid syndrome has been proven. The formation of neutrophil extracellular traps (not toz) is one of the pathophysiological mechanisms of the course of a new coronavirus infection. In addition, the effect of the ketosis process on the development of complications in the postcovid period has been proven. The article discusses the history of the term, various clinical manifestations of the postcovid period, as well as the role of innate immunity mechanisms at all stages of the course of a new coronavirus infection.
format Article
id doaj-art-e738d6a2a152401fbe46d0f6c83176ca
institution Kabale University
issn 2226-6704
2411-6564
language Russian
publishDate 2023-08-01
publisher SINAPS LLC
record_format Article
series Архивъ внутренней медицины
spelling doaj-art-e738d6a2a152401fbe46d0f6c83176ca2025-08-20T04:00:01ZrusSINAPS LLCАрхивъ внутренней медицины2226-67042411-65642023-08-0113426327110.20514/2226-6704-2023-13-4-263-271951The Role of the Innate Immune System in the Development of Postcovid Syndrome and its ComplicationsV. N. Larina0E. A. Stodelova1Zh. M. Salmasi2A. N. Kazimirskij3G. V. Porjadin4Pirogov Russian National Research Medical University, Department of Outpatient Therapy, Faculty of General MedicinePirogov Russian National Research Medical University, Department of Outpatient Therapy, Faculty of General MedicinePirogov Russian National Research Medical University, Department of Pathophysiology and Clinical Pathophysiology, Faculty of General MedicinePirogov Russian National Research Medical University, Department of Pathophysiology and Clinical Pathophysiology, Faculty of General MedicinePirogov Russian National Research Medical University, Department of Pathophysiology and Clinical Pathophysiology, Faculty of General MedicineTo date, the problem of preserving symptoms after recovery from a new coronavirus infection is urgent in the world. This condition is called postcovid syndrome. The clinical picture of postcovid syndrome has multiple manifestations: general, respiratory, cardiovascular, gastrointestinal, skin and other symptoms. At the moment, there are no laboratory criteria for the diagnosis of this condition, but the great role of neutrophils in the development of both acute disease and postcovid syndrome has been proven. The formation of neutrophil extracellular traps (not toz) is one of the pathophysiological mechanisms of the course of a new coronavirus infection. In addition, the effect of the ketosis process on the development of complications in the postcovid period has been proven. The article discusses the history of the term, various clinical manifestations of the postcovid period, as well as the role of innate immunity mechanisms at all stages of the course of a new coronavirus infection.https://www.medarhive.ru/jour/article/view/1637coronavirus infectioncovid-19postcovid syndromeextracellular neutrophil trapsnetosisnets
spellingShingle V. N. Larina
E. A. Stodelova
Zh. M. Salmasi
A. N. Kazimirskij
G. V. Porjadin
The Role of the Innate Immune System in the Development of Postcovid Syndrome and its Complications
Архивъ внутренней медицины
coronavirus infection
covid-19
postcovid syndrome
extracellular neutrophil traps
netosis
nets
title The Role of the Innate Immune System in the Development of Postcovid Syndrome and its Complications
title_full The Role of the Innate Immune System in the Development of Postcovid Syndrome and its Complications
title_fullStr The Role of the Innate Immune System in the Development of Postcovid Syndrome and its Complications
title_full_unstemmed The Role of the Innate Immune System in the Development of Postcovid Syndrome and its Complications
title_short The Role of the Innate Immune System in the Development of Postcovid Syndrome and its Complications
title_sort role of the innate immune system in the development of postcovid syndrome and its complications
topic coronavirus infection
covid-19
postcovid syndrome
extracellular neutrophil traps
netosis
nets
url https://www.medarhive.ru/jour/article/view/1637
work_keys_str_mv AT vnlarina theroleoftheinnateimmunesysteminthedevelopmentofpostcovidsyndromeanditscomplications
AT eastodelova theroleoftheinnateimmunesysteminthedevelopmentofpostcovidsyndromeanditscomplications
AT zhmsalmasi theroleoftheinnateimmunesysteminthedevelopmentofpostcovidsyndromeanditscomplications
AT ankazimirskij theroleoftheinnateimmunesysteminthedevelopmentofpostcovidsyndromeanditscomplications
AT gvporjadin theroleoftheinnateimmunesysteminthedevelopmentofpostcovidsyndromeanditscomplications
AT vnlarina roleoftheinnateimmunesysteminthedevelopmentofpostcovidsyndromeanditscomplications
AT eastodelova roleoftheinnateimmunesysteminthedevelopmentofpostcovidsyndromeanditscomplications
AT zhmsalmasi roleoftheinnateimmunesysteminthedevelopmentofpostcovidsyndromeanditscomplications
AT ankazimirskij roleoftheinnateimmunesysteminthedevelopmentofpostcovidsyndromeanditscomplications
AT gvporjadin roleoftheinnateimmunesysteminthedevelopmentofpostcovidsyndromeanditscomplications