QT Independent Ventricular Tachycardia Induced by Arsenic Trioxide

Arsenic trioxide (ATO) is commonly known to cause QT prolongation with resultant ventricular tachycardia (VT). VT, independent of QT prolongation, can be a complication of ATO. We present a 46-year-old female who received ATO and during her hospital course had intermittent nonsustained VT. All usual...

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Main Authors: Vicken Zeitjian, Carmel Moazez, Waqas Arslan, Mehrdad Saririan
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Cardiology
Online Access:http://dx.doi.org/10.1155/2019/9870283
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author Vicken Zeitjian
Carmel Moazez
Waqas Arslan
Mehrdad Saririan
author_facet Vicken Zeitjian
Carmel Moazez
Waqas Arslan
Mehrdad Saririan
author_sort Vicken Zeitjian
collection DOAJ
description Arsenic trioxide (ATO) is commonly known to cause QT prolongation with resultant ventricular tachycardia (VT). VT, independent of QT prolongation, can be a complication of ATO. We present a 46-year-old female who received ATO and during her hospital course had intermittent nonsustained VT. All usual causes of VT were considered including reduced EF<35%, ischemia, electrolyte abnormalities, medications, and genetic polymorphisms; however, no specific cause was found. After stopping therapy, the episodes of nonsustained VT ceased indicating that there is an association between ATO and VT.
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institution Kabale University
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language English
publishDate 2019-01-01
publisher Wiley
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series Case Reports in Cardiology
spelling doaj-art-e73645bd2917442c8011bd52f811f82e2025-08-20T03:26:14ZengWileyCase Reports in Cardiology2090-64042090-64122019-01-01201910.1155/2019/98702839870283QT Independent Ventricular Tachycardia Induced by Arsenic TrioxideVicken Zeitjian0Carmel Moazez1Waqas Arslan2Mehrdad Saririan3Department of Cardiovascular Diseases, University of Texas San Antonio Health Science Center, 7703 Floyd Curl Dr. San Antonio, TX 78229, USADepartment of Internal Medicine, Creighton University Maricopa Medical Center, 2601 E. Roosevelt St. Phoenix, AZ 85006, USADepartment of Hematology and Oncology, Creighton University Maricopa Medical Center, 2601 E. Roosevelt St. Phoenix, AZ 85006, USADepartment of Cardiovascular Diseases, Creighton University Maricopa Medical Center, 2601 E. Roosevelt St. Phoenix, AZ 85006, USAArsenic trioxide (ATO) is commonly known to cause QT prolongation with resultant ventricular tachycardia (VT). VT, independent of QT prolongation, can be a complication of ATO. We present a 46-year-old female who received ATO and during her hospital course had intermittent nonsustained VT. All usual causes of VT were considered including reduced EF<35%, ischemia, electrolyte abnormalities, medications, and genetic polymorphisms; however, no specific cause was found. After stopping therapy, the episodes of nonsustained VT ceased indicating that there is an association between ATO and VT.http://dx.doi.org/10.1155/2019/9870283
spellingShingle Vicken Zeitjian
Carmel Moazez
Waqas Arslan
Mehrdad Saririan
QT Independent Ventricular Tachycardia Induced by Arsenic Trioxide
Case Reports in Cardiology
title QT Independent Ventricular Tachycardia Induced by Arsenic Trioxide
title_full QT Independent Ventricular Tachycardia Induced by Arsenic Trioxide
title_fullStr QT Independent Ventricular Tachycardia Induced by Arsenic Trioxide
title_full_unstemmed QT Independent Ventricular Tachycardia Induced by Arsenic Trioxide
title_short QT Independent Ventricular Tachycardia Induced by Arsenic Trioxide
title_sort qt independent ventricular tachycardia induced by arsenic trioxide
url http://dx.doi.org/10.1155/2019/9870283
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AT waqasarslan qtindependentventriculartachycardiainducedbyarsenictrioxide
AT mehrdadsaririan qtindependentventriculartachycardiainducedbyarsenictrioxide