QT Independent Ventricular Tachycardia Induced by Arsenic Trioxide

Arsenic trioxide (ATO) is commonly known to cause QT prolongation with resultant ventricular tachycardia (VT). VT, independent of QT prolongation, can be a complication of ATO. We present a 46-year-old female who received ATO and during her hospital course had intermittent nonsustained VT. All usual...

Full description

Saved in:
Bibliographic Details
Main Authors: Vicken Zeitjian, Carmel Moazez, Waqas Arslan, Mehrdad Saririan
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Cardiology
Online Access:http://dx.doi.org/10.1155/2019/9870283
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Arsenic trioxide (ATO) is commonly known to cause QT prolongation with resultant ventricular tachycardia (VT). VT, independent of QT prolongation, can be a complication of ATO. We present a 46-year-old female who received ATO and during her hospital course had intermittent nonsustained VT. All usual causes of VT were considered including reduced EF<35%, ischemia, electrolyte abnormalities, medications, and genetic polymorphisms; however, no specific cause was found. After stopping therapy, the episodes of nonsustained VT ceased indicating that there is an association between ATO and VT.
ISSN:2090-6404
2090-6412