Effects of hypertensive disorders of pregnancy on the complications in very low birth weight neonates
Objective This study was designed to investigate the effects of hypertensive disorders of pregnancy (HDP) on the complications in very low birth weight (VLBW) neonates.Methods We retrospectively included VLBW neonates (<37 weeks) who were delivered by HDP pregnant women with a body weight of <...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2024-12-01
|
| Series: | Hypertension in Pregnancy |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/10641955.2024.2314576 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850117539294609408 |
|---|---|
| author | Baoquan Zhang Xiujuan Chen Changyi Yang Huiying Shi Wenlong Xiu |
| author_facet | Baoquan Zhang Xiujuan Chen Changyi Yang Huiying Shi Wenlong Xiu |
| author_sort | Baoquan Zhang |
| collection | DOAJ |
| description | Objective This study was designed to investigate the effects of hypertensive disorders of pregnancy (HDP) on the complications in very low birth weight (VLBW) neonates.Methods We retrospectively included VLBW neonates (<37 weeks) who were delivered by HDP pregnant women with a body weight of < 1,500 g (HDP group) hospitalized in our hospital between January 2016 and July 2021. Gestational age matched VLBW neonates delivered by pregnant women with a normal blood pressure, with a proportion of 1:1 to the HDP group in number, served as normal control.Results Then we compared the peripartum data and major complications between HDP group and control. The body weight, prelabor rupture of membrane (PROM), maternal age, cesarean section rate, fetal distress, small for gestational age (SGA), mechanical ventilation, RDS, necrotizing enterocolitis (NEC) (≥2 stage), Apgar score at 1 min, and mortality in HDP group showed statistical differences compared with those of the control (all p < 0.05). To compare the major complications among HDP subgroups, we classified the VLBW neonates of the HDP group into three subgroups including gestational hypertension group (n = 72), pre-eclampsia (PE) group (n = 222), and eclampsia group (n = 14), which showed significant differences in the fetal distress, Apgar score at 1 min, SGA, ventilation, RDS and NEC (≥2 stage) among these subgroups (all p < 0.05). Multivariate regression analysis showed that eclampsia and PE were the independent risk factors for SGA and NEC, respectively.Conclusion HDP was associated with increased incidence of neonatal asphyxia, fatal distress, SGA, mechanical ventilation, RDS, NEC and mortality. Besides, eclampsia and PE were independent risk factors for SGA and NEC. |
| format | Article |
| id | doaj-art-e7335de36f3d422090d2bb3dd7830925 |
| institution | OA Journals |
| issn | 1064-1955 1525-6065 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Hypertension in Pregnancy |
| spelling | doaj-art-e7335de36f3d422090d2bb3dd78309252025-08-20T02:36:04ZengTaylor & Francis GroupHypertension in Pregnancy1064-19551525-60652024-12-0143110.1080/10641955.2024.2314576Effects of hypertensive disorders of pregnancy on the complications in very low birth weight neonatesBaoquan Zhang0Xiujuan Chen1Changyi Yang2Huiying Shi3Wenlong Xiu4Neonatology Department, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, ChinaNeonatology Department, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, ChinaNeonatology Department, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, ChinaNeonatology Department, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, ChinaNeonatology Department, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, ChinaObjective This study was designed to investigate the effects of hypertensive disorders of pregnancy (HDP) on the complications in very low birth weight (VLBW) neonates.Methods We retrospectively included VLBW neonates (<37 weeks) who were delivered by HDP pregnant women with a body weight of < 1,500 g (HDP group) hospitalized in our hospital between January 2016 and July 2021. Gestational age matched VLBW neonates delivered by pregnant women with a normal blood pressure, with a proportion of 1:1 to the HDP group in number, served as normal control.Results Then we compared the peripartum data and major complications between HDP group and control. The body weight, prelabor rupture of membrane (PROM), maternal age, cesarean section rate, fetal distress, small for gestational age (SGA), mechanical ventilation, RDS, necrotizing enterocolitis (NEC) (≥2 stage), Apgar score at 1 min, and mortality in HDP group showed statistical differences compared with those of the control (all p < 0.05). To compare the major complications among HDP subgroups, we classified the VLBW neonates of the HDP group into three subgroups including gestational hypertension group (n = 72), pre-eclampsia (PE) group (n = 222), and eclampsia group (n = 14), which showed significant differences in the fetal distress, Apgar score at 1 min, SGA, ventilation, RDS and NEC (≥2 stage) among these subgroups (all p < 0.05). Multivariate regression analysis showed that eclampsia and PE were the independent risk factors for SGA and NEC, respectively.Conclusion HDP was associated with increased incidence of neonatal asphyxia, fatal distress, SGA, mechanical ventilation, RDS, NEC and mortality. Besides, eclampsia and PE were independent risk factors for SGA and NEC.https://www.tandfonline.com/doi/10.1080/10641955.2024.2314576Hypertensive disorders of pregnancyhypertensionpre-eclampsiaeclampsiavery low birth weight neonate |
| spellingShingle | Baoquan Zhang Xiujuan Chen Changyi Yang Huiying Shi Wenlong Xiu Effects of hypertensive disorders of pregnancy on the complications in very low birth weight neonates Hypertension in Pregnancy Hypertensive disorders of pregnancy hypertension pre-eclampsia eclampsia very low birth weight neonate |
| title | Effects of hypertensive disorders of pregnancy on the complications in very low birth weight neonates |
| title_full | Effects of hypertensive disorders of pregnancy on the complications in very low birth weight neonates |
| title_fullStr | Effects of hypertensive disorders of pregnancy on the complications in very low birth weight neonates |
| title_full_unstemmed | Effects of hypertensive disorders of pregnancy on the complications in very low birth weight neonates |
| title_short | Effects of hypertensive disorders of pregnancy on the complications in very low birth weight neonates |
| title_sort | effects of hypertensive disorders of pregnancy on the complications in very low birth weight neonates |
| topic | Hypertensive disorders of pregnancy hypertension pre-eclampsia eclampsia very low birth weight neonate |
| url | https://www.tandfonline.com/doi/10.1080/10641955.2024.2314576 |
| work_keys_str_mv | AT baoquanzhang effectsofhypertensivedisordersofpregnancyonthecomplicationsinverylowbirthweightneonates AT xiujuanchen effectsofhypertensivedisordersofpregnancyonthecomplicationsinverylowbirthweightneonates AT changyiyang effectsofhypertensivedisordersofpregnancyonthecomplicationsinverylowbirthweightneonates AT huiyingshi effectsofhypertensivedisordersofpregnancyonthecomplicationsinverylowbirthweightneonates AT wenlongxiu effectsofhypertensivedisordersofpregnancyonthecomplicationsinverylowbirthweightneonates |