Prevalence of Types TEM, SHV and CTX-M /3LES Among Pathogens of Chronic Pyelonephritis
There Is lately observed an increase in the resistance of the main pathogens of urologie infection to β-lactam antibiotics due to production of plasmid-induced в-lactamases. The aim of the study was to reveal types TEM, SHV and CTX-M plasmid β-lactamases among uropathogens. Out of 115 isolates, 30 (...
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| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
LLC "Publishing House OKI"
2020-05-01
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| Series: | Антибиотики и Химиотерапия |
| Subjects: | |
| Online Access: | https://www.antibiotics-chemotherapy.ru/jour/article/view/576 |
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| Summary: | There Is lately observed an increase in the resistance of the main pathogens of urologie infection to β-lactam antibiotics due to production of plasmid-induced в-lactamases. The aim of the study was to reveal types TEM, SHV and CTX-M plasmid β-lactamases among uropathogens. Out of 115 isolates, 30 (26.1%) strains produced β-lactamases. Genes blaTEM and blaCTX-Mwere the most frequent. Most of the isolates were resistant to ampicillin (73.3%), ciprofloxacin (46.7%), levofloxacin (43.3%), gentamicin (40%). The βLES-producing strains were susceptible to meropenem (96.7%), nitroxolin (83.3%), phosphomycin (70%), amikacin (70%). The presence of the resistance genes in the uropathogens was evident of a high rate of their distribution among them by the plasmids. Detection of the plasmid-induced β-lactamases is important for the optimal choice of the antibiotic for empirical therapy. |
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| ISSN: | 0235-2990 |