Persistent fatty acid catabolism during plant oil synthesis
Summary: Plant lipids are an essential energy source for diets and are a sustainable alternative to petroleum-based fuels and feedstocks. Fatty acid breakdown during seed germination is crucial for seedling establishment but unexpected during seed filling. Here, we demonstrate that the simultaneous...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-04-01
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| Series: | Cell Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124725002633 |
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| author | Somnath Koley Poonam Jyoti Maneesh Lingwan Michael Wei Chunhui Xu Kevin L. Chu Russell B. Williams Abraham J. Koo Jay J. Thelen Dong Xu Doug K. Allen |
| author_facet | Somnath Koley Poonam Jyoti Maneesh Lingwan Michael Wei Chunhui Xu Kevin L. Chu Russell B. Williams Abraham J. Koo Jay J. Thelen Dong Xu Doug K. Allen |
| author_sort | Somnath Koley |
| collection | DOAJ |
| description | Summary: Plant lipids are an essential energy source for diets and are a sustainable alternative to petroleum-based fuels and feedstocks. Fatty acid breakdown during seed germination is crucial for seedling establishment but unexpected during seed filling. Here, we demonstrate that the simultaneous biosynthesis and degradation of fatty acids begins early and continues across all phases of oil filling and throughout the photoperiod. Tests in camelina, rapeseed, and an engineered high-oil tobacco line confirmed that concomitant synthesis and breakdown in oil-producing tissues over development is the rule rather than the exception. Furthermore, we show that transgenics, designed to elevate fatty acid biosynthesis, failed to achieve anticipated increases in storage lipid levels due to increased degradation, potentially explaining the underperformance of engineered lines compared to expectations more generally. |
| format | Article |
| id | doaj-art-e72cae1cb42142328b579bcf3895896d |
| institution | DOAJ |
| issn | 2211-1247 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Cell Reports |
| spelling | doaj-art-e72cae1cb42142328b579bcf3895896d2025-08-20T02:49:25ZengElsevierCell Reports2211-12472025-04-0144411549210.1016/j.celrep.2025.115492Persistent fatty acid catabolism during plant oil synthesisSomnath Koley0Poonam Jyoti1Maneesh Lingwan2Michael Wei3Chunhui Xu4Kevin L. Chu5Russell B. Williams6Abraham J. Koo7Jay J. Thelen8Dong Xu9Doug K. Allen10Donald Danforth Plant Science Center, St. Louis, MO 63132, USA; Corresponding authorDonald Danforth Plant Science Center, St. Louis, MO 63132, USADonald Danforth Plant Science Center, St. Louis, MO 63132, USADonald Danforth Plant Science Center, St. Louis, MO 63132, USADepartment of Electrical Engineering and Computer Science, University of Missouri, Columbia, MO 65211, USA; Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USADonald Danforth Plant Science Center, St. Louis, MO 63132, USADonald Danforth Plant Science Center, St. Louis, MO 63132, USADepartment of Biochemistry, University of Missouri, Columbia, MO 65211, USAChristopher S. Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA; Department of Biochemistry, University of Missouri, Columbia, MO 65211, USADepartment of Electrical Engineering and Computer Science, University of Missouri, Columbia, MO 65211, USA; Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USADonald Danforth Plant Science Center, St. Louis, MO 63132, USA; US Department of Agriculture-Agricultural Research Service, St. Louis, MO 63132, USA; Corresponding authorSummary: Plant lipids are an essential energy source for diets and are a sustainable alternative to petroleum-based fuels and feedstocks. Fatty acid breakdown during seed germination is crucial for seedling establishment but unexpected during seed filling. Here, we demonstrate that the simultaneous biosynthesis and degradation of fatty acids begins early and continues across all phases of oil filling and throughout the photoperiod. Tests in camelina, rapeseed, and an engineered high-oil tobacco line confirmed that concomitant synthesis and breakdown in oil-producing tissues over development is the rule rather than the exception. Furthermore, we show that transgenics, designed to elevate fatty acid biosynthesis, failed to achieve anticipated increases in storage lipid levels due to increased degradation, potentially explaining the underperformance of engineered lines compared to expectations more generally.http://www.sciencedirect.com/science/article/pii/S2211124725002633CP: Plants |
| spellingShingle | Somnath Koley Poonam Jyoti Maneesh Lingwan Michael Wei Chunhui Xu Kevin L. Chu Russell B. Williams Abraham J. Koo Jay J. Thelen Dong Xu Doug K. Allen Persistent fatty acid catabolism during plant oil synthesis Cell Reports CP: Plants |
| title | Persistent fatty acid catabolism during plant oil synthesis |
| title_full | Persistent fatty acid catabolism during plant oil synthesis |
| title_fullStr | Persistent fatty acid catabolism during plant oil synthesis |
| title_full_unstemmed | Persistent fatty acid catabolism during plant oil synthesis |
| title_short | Persistent fatty acid catabolism during plant oil synthesis |
| title_sort | persistent fatty acid catabolism during plant oil synthesis |
| topic | CP: Plants |
| url | http://www.sciencedirect.com/science/article/pii/S2211124725002633 |
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