Collaboration within the global vaccine safety surveillance ecosystem during the COVID-19 pandemic: lessons learnt and key recommendations from the COVAX Vaccine Safety Working Group

This analysis describes the successes, challenges and opportunities to improve global vaccine safety surveillance as observed by the Vaccine Safety Working Group from its role as a platform of exchange for stakeholders responsible for monitoring the safety of vaccines distributed through the COVAX m...

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Main Authors: Rebecca E Chandler, James Milligan, Emmanuelle Espie, Katharina Hartmann, Madhava Ram Balakrishnan, Daniel Brasseur, Philip Bryan, Corinne Jouquelet-Royer, Linda Nesbitt, Shanthi Pal, Alexander Precioso, Paulo Takey, Robert T Chen
Format: Article
Language:English
Published: BMJ Publishing Group 2024-03-01
Series:BMJ Global Health
Online Access:https://gh.bmj.com/content/9/3/e014544.full
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author Rebecca E Chandler
James Milligan
Emmanuelle Espie
Katharina Hartmann
Madhava Ram Balakrishnan
Daniel Brasseur
Philip Bryan
Corinne Jouquelet-Royer
Linda Nesbitt
Shanthi Pal
Alexander Precioso
Paulo Takey
Robert T Chen
author_facet Rebecca E Chandler
James Milligan
Emmanuelle Espie
Katharina Hartmann
Madhava Ram Balakrishnan
Daniel Brasseur
Philip Bryan
Corinne Jouquelet-Royer
Linda Nesbitt
Shanthi Pal
Alexander Precioso
Paulo Takey
Robert T Chen
author_sort Rebecca E Chandler
collection DOAJ
description This analysis describes the successes, challenges and opportunities to improve global vaccine safety surveillance as observed by the Vaccine Safety Working Group from its role as a platform of exchange for stakeholders responsible for monitoring the safety of vaccines distributed through the COVAX mechanism. Three key elements considered to be essential for ongoing and future pandemic preparedness for vaccine developers in their interaction with other members of the vaccine safety ecosystem are (1) the availability of infrastructure and capacity for active vaccine safety surveillance in low-income and middle-income countries (LMICs), including the advancement of concepts of safety surveillance and risk management to vaccine developers and manufacturers from LMICs; (2) more comprehensive mechanisms to ensure timely exchange of vaccine safety data and/or knowledge gaps between public health authorities and vaccine developers and manufacturers; and (3) further implementation of the concept of regulatory reliance in pharmacovigilance. These aims would both conserve valuable resources and allow for more equitable access to vaccine safety information and for benefit/risk decision-making.
format Article
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issn 2059-7908
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spelling doaj-art-e72c4727d6544d8c81ab20090652d1a92025-08-20T02:50:49ZengBMJ Publishing GroupBMJ Global Health2059-79082024-03-019310.1136/bmjgh-2023-014544Collaboration within the global vaccine safety surveillance ecosystem during the COVID-19 pandemic: lessons learnt and key recommendations from the COVAX Vaccine Safety Working GroupRebecca E Chandler0James Milligan1Emmanuelle Espie2Katharina Hartmann3Madhava Ram Balakrishnan4Daniel Brasseur5Philip Bryan6Corinne Jouquelet-Royer7Linda Nesbitt8Shanthi Pal9Alexander Precioso10Paulo Takey11Robert T Chen121 Coalition for Epidemic Preparedness Innovations, Oslo, Norway7 CSL Seqirus, Maidenhead, UK1 Coalition for Epidemic Preparedness Innovations, Oslo, Norway5 Independent Advisor, Zurich, Switzerland2 WHO, Geneva, Switzerland3 Independent Advisor, Brussels, Belgium4 P95 Epidemiology and Pharmacovigilance, Leuven, Belgium6 Sanofi Pasteur, Lyon, France8 Biovac Institute, Pinelands, Cape Town, South Africa2 WHO, Geneva, Switzerland9 Instituto Butantan, São Paulo, Brazil10 Bio-Manguinhos, Rio de Janeiro, Brazil11 The Task Force for Global Health, Decatur, Georgia, USAThis analysis describes the successes, challenges and opportunities to improve global vaccine safety surveillance as observed by the Vaccine Safety Working Group from its role as a platform of exchange for stakeholders responsible for monitoring the safety of vaccines distributed through the COVAX mechanism. Three key elements considered to be essential for ongoing and future pandemic preparedness for vaccine developers in their interaction with other members of the vaccine safety ecosystem are (1) the availability of infrastructure and capacity for active vaccine safety surveillance in low-income and middle-income countries (LMICs), including the advancement of concepts of safety surveillance and risk management to vaccine developers and manufacturers from LMICs; (2) more comprehensive mechanisms to ensure timely exchange of vaccine safety data and/or knowledge gaps between public health authorities and vaccine developers and manufacturers; and (3) further implementation of the concept of regulatory reliance in pharmacovigilance. These aims would both conserve valuable resources and allow for more equitable access to vaccine safety information and for benefit/risk decision-making.https://gh.bmj.com/content/9/3/e014544.full
spellingShingle Rebecca E Chandler
James Milligan
Emmanuelle Espie
Katharina Hartmann
Madhava Ram Balakrishnan
Daniel Brasseur
Philip Bryan
Corinne Jouquelet-Royer
Linda Nesbitt
Shanthi Pal
Alexander Precioso
Paulo Takey
Robert T Chen
Collaboration within the global vaccine safety surveillance ecosystem during the COVID-19 pandemic: lessons learnt and key recommendations from the COVAX Vaccine Safety Working Group
BMJ Global Health
title Collaboration within the global vaccine safety surveillance ecosystem during the COVID-19 pandemic: lessons learnt and key recommendations from the COVAX Vaccine Safety Working Group
title_full Collaboration within the global vaccine safety surveillance ecosystem during the COVID-19 pandemic: lessons learnt and key recommendations from the COVAX Vaccine Safety Working Group
title_fullStr Collaboration within the global vaccine safety surveillance ecosystem during the COVID-19 pandemic: lessons learnt and key recommendations from the COVAX Vaccine Safety Working Group
title_full_unstemmed Collaboration within the global vaccine safety surveillance ecosystem during the COVID-19 pandemic: lessons learnt and key recommendations from the COVAX Vaccine Safety Working Group
title_short Collaboration within the global vaccine safety surveillance ecosystem during the COVID-19 pandemic: lessons learnt and key recommendations from the COVAX Vaccine Safety Working Group
title_sort collaboration within the global vaccine safety surveillance ecosystem during the covid 19 pandemic lessons learnt and key recommendations from the covax vaccine safety working group
url https://gh.bmj.com/content/9/3/e014544.full
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