Heart Rate Variability and Cardiovascular Reflex Tests for Assessment of Autonomic Functions in Preeclampsia
Alterations in the autonomic cardiovascular control have been implicated to play an important etiologic role in preeclampsia. The present study was designed to evaluate autonomic functions in preeclamptic pregnant women and compare the values with normotensive pregnant and healthy nonpregnant contro...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2018-01-01
|
| Series: | International Journal of Hypertension |
| Online Access: | http://dx.doi.org/10.1155/2018/8163824 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850167567635709952 |
|---|---|
| author | Meenakshi Chaswal Raj Kapoor Achla Batra Savita Verma Bhupendra S. Yadav |
| author_facet | Meenakshi Chaswal Raj Kapoor Achla Batra Savita Verma Bhupendra S. Yadav |
| author_sort | Meenakshi Chaswal |
| collection | DOAJ |
| description | Alterations in the autonomic cardiovascular control have been implicated to play an important etiologic role in preeclampsia. The present study was designed to evaluate autonomic functions in preeclamptic pregnant women and compare the values with normotensive pregnant and healthy nonpregnant controls. Assessment of autonomic functions was done by cardiovascular reflex tests and by analysis of heart rate variability (HRV). Cardiovascular reflex tests included deep breathing test (DBT) and lying to standing test (LST). HRV was analyzed in both time and frequency domain for quantifying the tone of autonomic nervous system to the heart. The time domain measures included standard deviation of normal R-R intervals (SDNN) and square root of mean squared differences of successive R-R intervals (RMSSD). In the frequency domain we measured total power (TP), high frequency (HF) power, low frequency (LF) power, and LF/HF ratio. Cardiovascular reflex tests showed a significant parasympathetic deficit in preeclamptic women. Among parameters of HRV, preeclamptic group had lower values of SDNN, RMSSD, TP, HF, and LF (ms2) and higher value of LF in normalised units along with high LF/HF ratio compared to normotensive pregnant and nonpregnant controls. Furthermore, normotensive pregnant women had lower values of SDNN, TP, and LF component in both absolute power and normalised units compared to nonpregnant females. The results confirm that normal pregnancy is associated with autonomic disturbances which get exaggerated in the state of preeclampsia. |
| format | Article |
| id | doaj-art-e72c0f98a2f049d2815c80e3279bc168 |
| institution | OA Journals |
| issn | 2090-0384 2090-0392 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Hypertension |
| spelling | doaj-art-e72c0f98a2f049d2815c80e3279bc1682025-08-20T02:21:10ZengWileyInternational Journal of Hypertension2090-03842090-03922018-01-01201810.1155/2018/81638248163824Heart Rate Variability and Cardiovascular Reflex Tests for Assessment of Autonomic Functions in PreeclampsiaMeenakshi Chaswal0Raj Kapoor1Achla Batra2Savita Verma3Bhupendra S. Yadav4Department of Physiology, VMMC and Safdarjung Hospital, New Delhi, IndiaDepartment of Physiology, VMMC and Safdarjung Hospital, New Delhi, IndiaDepartment of Obstetrics and Gynaecology, VMMC and Safdarjung Hospital, New Delhi, IndiaDepartment of Obstetrics and Gynaecology, SHMMH Medical college, Saharanpur, UP, IndiaDepartment of Physiology, BHU, Uttar Pradesh, IndiaAlterations in the autonomic cardiovascular control have been implicated to play an important etiologic role in preeclampsia. The present study was designed to evaluate autonomic functions in preeclamptic pregnant women and compare the values with normotensive pregnant and healthy nonpregnant controls. Assessment of autonomic functions was done by cardiovascular reflex tests and by analysis of heart rate variability (HRV). Cardiovascular reflex tests included deep breathing test (DBT) and lying to standing test (LST). HRV was analyzed in both time and frequency domain for quantifying the tone of autonomic nervous system to the heart. The time domain measures included standard deviation of normal R-R intervals (SDNN) and square root of mean squared differences of successive R-R intervals (RMSSD). In the frequency domain we measured total power (TP), high frequency (HF) power, low frequency (LF) power, and LF/HF ratio. Cardiovascular reflex tests showed a significant parasympathetic deficit in preeclamptic women. Among parameters of HRV, preeclamptic group had lower values of SDNN, RMSSD, TP, HF, and LF (ms2) and higher value of LF in normalised units along with high LF/HF ratio compared to normotensive pregnant and nonpregnant controls. Furthermore, normotensive pregnant women had lower values of SDNN, TP, and LF component in both absolute power and normalised units compared to nonpregnant females. The results confirm that normal pregnancy is associated with autonomic disturbances which get exaggerated in the state of preeclampsia.http://dx.doi.org/10.1155/2018/8163824 |
| spellingShingle | Meenakshi Chaswal Raj Kapoor Achla Batra Savita Verma Bhupendra S. Yadav Heart Rate Variability and Cardiovascular Reflex Tests for Assessment of Autonomic Functions in Preeclampsia International Journal of Hypertension |
| title | Heart Rate Variability and Cardiovascular Reflex Tests for Assessment of Autonomic Functions in Preeclampsia |
| title_full | Heart Rate Variability and Cardiovascular Reflex Tests for Assessment of Autonomic Functions in Preeclampsia |
| title_fullStr | Heart Rate Variability and Cardiovascular Reflex Tests for Assessment of Autonomic Functions in Preeclampsia |
| title_full_unstemmed | Heart Rate Variability and Cardiovascular Reflex Tests for Assessment of Autonomic Functions in Preeclampsia |
| title_short | Heart Rate Variability and Cardiovascular Reflex Tests for Assessment of Autonomic Functions in Preeclampsia |
| title_sort | heart rate variability and cardiovascular reflex tests for assessment of autonomic functions in preeclampsia |
| url | http://dx.doi.org/10.1155/2018/8163824 |
| work_keys_str_mv | AT meenakshichaswal heartratevariabilityandcardiovascularreflextestsforassessmentofautonomicfunctionsinpreeclampsia AT rajkapoor heartratevariabilityandcardiovascularreflextestsforassessmentofautonomicfunctionsinpreeclampsia AT achlabatra heartratevariabilityandcardiovascularreflextestsforassessmentofautonomicfunctionsinpreeclampsia AT savitaverma heartratevariabilityandcardiovascularreflextestsforassessmentofautonomicfunctionsinpreeclampsia AT bhupendrasyadav heartratevariabilityandcardiovascularreflextestsforassessmentofautonomicfunctionsinpreeclampsia |