Adaptive Fractional Order Control for Bispectral Index Regulation During Anaesthesia
Human error remains a significant concern in the medical field, particularly in anaesthesia, where even minor miscalculations can jeopardise patient safety. To address these challenges, the integration of automated control systems has emerged as a viable solution. Most existing control algorithms ar...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-05-01
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| Series: | Fractal and Fractional |
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| Online Access: | https://www.mdpi.com/2504-3110/9/6/330 |
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| author | Alin-Ciprian Malița Cristina Ioana Muresan Manuel A. Duarte-Mermoud Gustavo Ceballos Benavides |
| author_facet | Alin-Ciprian Malița Cristina Ioana Muresan Manuel A. Duarte-Mermoud Gustavo Ceballos Benavides |
| author_sort | Alin-Ciprian Malița |
| collection | DOAJ |
| description | Human error remains a significant concern in the medical field, particularly in anaesthesia, where even minor miscalculations can jeopardise patient safety. To address these challenges, the integration of automated control systems has emerged as a viable solution. Most existing control algorithms are tuned using a nominal patient model and inter-patient variability is tackled by incorporating robustness in the controller design. A personalised approach is, however, desirable. In this paper, a hybrid control framework that combines fractional-order control with a model-reference adaptive control (MRAC) approach is proposed as a solution for personalised control of the bispectral index (BIS). The system is designed to meet stringent performance requirements while ensuring stability and robustness. Comparative result with a non-adaptive fractional order controller are presented to demonstrate the efficiency of the proposed adaptive strategy. Simulation results demonstrate promising outcomes, both with respect to the selected criteria and in alignment with the anticipated future developments. |
| format | Article |
| id | doaj-art-e72917e0624e4f279893562fc03fcaa9 |
| institution | OA Journals |
| issn | 2504-3110 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Fractal and Fractional |
| spelling | doaj-art-e72917e0624e4f279893562fc03fcaa92025-08-20T02:21:01ZengMDPI AGFractal and Fractional2504-31102025-05-019633010.3390/fractalfract9060330Adaptive Fractional Order Control for Bispectral Index Regulation During AnaesthesiaAlin-Ciprian Malița0Cristina Ioana Muresan1Manuel A. Duarte-Mermoud2Gustavo Ceballos Benavides3Department of Automation, Technical University of Cluj-Napoca, Memorandumului Street No. 28, 400114 Cluj-Napoca, RomaniaDepartment of Automation, Technical University of Cluj-Napoca, Memorandumului Street No. 28, 400114 Cluj-Napoca, RomaniaFacultad de Ingeniería y Arquitectura, Universidad Central de Chile, Av. Santa Isabel 1186, Santiago 8330601, Región Metropolitana, ChileFacultad de Ingeniería y Arquitectura, Universidad Central de Chile, Av. Santa Isabel 1186, Santiago 8330601, Región Metropolitana, ChileHuman error remains a significant concern in the medical field, particularly in anaesthesia, where even minor miscalculations can jeopardise patient safety. To address these challenges, the integration of automated control systems has emerged as a viable solution. Most existing control algorithms are tuned using a nominal patient model and inter-patient variability is tackled by incorporating robustness in the controller design. A personalised approach is, however, desirable. In this paper, a hybrid control framework that combines fractional-order control with a model-reference adaptive control (MRAC) approach is proposed as a solution for personalised control of the bispectral index (BIS). The system is designed to meet stringent performance requirements while ensuring stability and robustness. Comparative result with a non-adaptive fractional order controller are presented to demonstrate the efficiency of the proposed adaptive strategy. Simulation results demonstrate promising outcomes, both with respect to the selected criteria and in alignment with the anticipated future developments.https://www.mdpi.com/2504-3110/9/6/330bispectral indexanaesthesiapropofolfractional-order controladaptive control systemclosed-loop control |
| spellingShingle | Alin-Ciprian Malița Cristina Ioana Muresan Manuel A. Duarte-Mermoud Gustavo Ceballos Benavides Adaptive Fractional Order Control for Bispectral Index Regulation During Anaesthesia Fractal and Fractional bispectral index anaesthesia propofol fractional-order control adaptive control system closed-loop control |
| title | Adaptive Fractional Order Control for Bispectral Index Regulation During Anaesthesia |
| title_full | Adaptive Fractional Order Control for Bispectral Index Regulation During Anaesthesia |
| title_fullStr | Adaptive Fractional Order Control for Bispectral Index Regulation During Anaesthesia |
| title_full_unstemmed | Adaptive Fractional Order Control for Bispectral Index Regulation During Anaesthesia |
| title_short | Adaptive Fractional Order Control for Bispectral Index Regulation During Anaesthesia |
| title_sort | adaptive fractional order control for bispectral index regulation during anaesthesia |
| topic | bispectral index anaesthesia propofol fractional-order control adaptive control system closed-loop control |
| url | https://www.mdpi.com/2504-3110/9/6/330 |
| work_keys_str_mv | AT alinciprianmalita adaptivefractionalordercontrolforbispectralindexregulationduringanaesthesia AT cristinaioanamuresan adaptivefractionalordercontrolforbispectralindexregulationduringanaesthesia AT manueladuartemermoud adaptivefractionalordercontrolforbispectralindexregulationduringanaesthesia AT gustavoceballosbenavides adaptivefractionalordercontrolforbispectralindexregulationduringanaesthesia |