Decoding the striatum of drug-naive patients with obsessive-compulsive disorder: a transcriptome and longitudinal functional magnetic resonance imaging study

Decoding the striatum of drug-naive patients with obsessive-compulsive disorder: a transcriptome and longitudinal functional magnetic resonance imaging study

Abstract The striatum’s role in obsessive-compulsive disorder (OCD) pathology is recognized. However, the specific contributions of individual striatal subregions (SSs) to OCD pathology are underexplored. We recruited 49 drug-naive OCD patients and 53 healthy controls, conducting clinical assessment...

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Main Authors: Yiding Han, Haohao Yan, Xiaoxiao Shan, Huabing Li, Feng Liu, Ping Li, Dongsheng Lv, Jingping Zhao, Wenbin Guo
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-025-03475-4
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