Patient-derived induced pluripotent stem cell organoids for amyotrophic lateral sclerosis drug discovery

Patient-derived induced pluripotent stem cell organoids for amyotrophic lateral sclerosis drug discovery

Complex biological mechanisms and unidentified therapeutic targets for amyotrophic lateral sclerosis (ALS) significantly hinder the development of effective treatments. Given these challenges, reliable disease models that accurately replicate ALS phenotypes with relevant biological underpinnings are...

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Bibliographic Details
Main Authors: Wenyan Li, Jingqi Liu, Wenting Li, Lina Sun, Hao Zhang, Lei Gao, Chong Gao
Format: Article
Language:English
Published: Compuscript Ltd 2025-01-01
Series:Acta Materia Medica
Online Access:https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2024-0077
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